N-heptadecylethanolamine | 13436-74-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-heptadecylethanolamine
• 英文别名: 2-(Heptadecylamino)ethan-1-ol；2-(heptadecylamino)ethanol
• CAS: 13436-74-3
• 化学式: C₁₉H₄₁NO
• 分子量: 299.541
• InChiKey: WJWSZYHMGMSQET-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  21
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  32.3
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N,O-bis(trimethylsilyl)trifluoroacetamide 、 N-heptadecylethanolamine 反应 1.0h， 生成 Heptadecyl-(2-trimethylsilanyloxy-ethyl)-amine
  参考文献：
  名称：

  Evidence for the reactivity of fatty aldehydes released from oxidized plasmalogens with phosphatidylethanolamine to form Schiff base adducts in rat brain homogenates

  摘要：

  The vinyl ether bond of plasmalogens could be among the first target of free radicals attack. Consequently, because of their location in the membranes of cells, plasmalogens represent a first shield against oxidative damages by protecting other macromolecules and are often considered as antioxidant molecules. However, under oxidative conditions their disruption leads to the release of fatty aldehydes. In this paper, we showed using gas chromatography-mass spectrometry (GC-MS) analyses that fatty aldehydes released from plasmalogens after oxidation (UV irradiation and Fe2+ /ascorbate) of cerebral cortex homogenates can generate covalent modifications of endogenous macromolecules such as phosphatidylethanolamine (PE), like the very reactive and toxic malondialdehyde (NIDA) and 4-hydroxynonenal (4-HNE). These newly formed Schiff base adducts could be responsible for deleterious effects on cells thus making the protective role of plasmalogens potentially questionable. (C) 2004 Elsevier Ireland Ltd. All rights reserved.

  DOI：

  10.1016/j.chemphyslip.2004.04.008
• 作为产物：
  描述：

  十七碳醛 在 sodium hydroxide 、 sodium cyanoborohydride 作用下， 以 甲醇 、 氯仿 为溶剂， 反应 5.0h， 生成 N-heptadecylethanolamine
  参考文献：
  名称：

  Evidence for the reactivity of fatty aldehydes released from oxidized plasmalogens with phosphatidylethanolamine to form Schiff base adducts in rat brain homogenates

  摘要：

  The vinyl ether bond of plasmalogens could be among the first target of free radicals attack. Consequently, because of their location in the membranes of cells, plasmalogens represent a first shield against oxidative damages by protecting other macromolecules and are often considered as antioxidant molecules. However, under oxidative conditions their disruption leads to the release of fatty aldehydes. In this paper, we showed using gas chromatography-mass spectrometry (GC-MS) analyses that fatty aldehydes released from plasmalogens after oxidation (UV irradiation and Fe2+ /ascorbate) of cerebral cortex homogenates can generate covalent modifications of endogenous macromolecules such as phosphatidylethanolamine (PE), like the very reactive and toxic malondialdehyde (NIDA) and 4-hydroxynonenal (4-HNE). These newly formed Schiff base adducts could be responsible for deleterious effects on cells thus making the protective role of plasmalogens potentially questionable. (C) 2004 Elsevier Ireland Ltd. All rights reserved.

  DOI：

  10.1016/j.chemphyslip.2004.04.008

文献信息

• Substituierte Aminoalkanolphospholipide und Verfahren zu ihrer Herstellung
  申请人：A. Nattermann & Cie. GmbH

  公开号：EP0107120A1

  公开（公告）日：1984-05-02

  Die Erfindung betrifft neue substituierte Aminoalkanolphospholipide der allgemeinen Formel 1 und Verfahren zu ihrer Herstellung. Die Verbindungen zeigen starke biologische Aktivität und können z.B. in Arzneimitteln und im Pflanzenschutz eingesetzt werden. Sie besitzen z.B. blutdrucksenkende, entzündungshemmende. tumorhemmende und antiatherosklerotische Eigenschaften.

  本发明涉及通式 1 的新型取代氨基烷醇磷脂及其制备工艺。 及其制备工艺。这些化合物具有很强的生物活性，可用于制药和植物保护等领域。例如，它们具有抗高血压、抗炎、抗肿瘤和抗动脉粥样硬化的特性。
• ANTISTATIC NON-CROSSLINKED FOAMED POLYETHYLENE RESIN PARTICLES AND MOLDED NON-CROSSLINKED FOAMED POLYETHYLENE RESIN BODY
  申请人：Kaneka Corporation

  公开号：EP2733164A1

  公开（公告）日：2014-05-21

  Provided are non-crosslinked foamed polyethylene resin particles that have a bulk density BD of 10 g/L or more and 100 g/L or less and are obtained by foaming polyethylene resin particles containing an antistatic agent in an amount of 0.1 part by weight or more and 3 parts by weight or less with respect to 100 parts by weight of a polyethylene resin and having a density of 0.920 g/cm3 or more and less than 0.940 g/cm3, and the non-crosslinked foamed polyethylene resin particles have a shrinkage ratio of 3% or more and 30% or less determined in accordance with Formula (1). The non-crosslinked foamed polyethylene resin particles can simply afford an antistatic molded non-crosslinked foamed polyethylene resin body that has a small shrinkage ratio with respect to mold dimension, is deformed in a small degree, and has good surface stretch. Shrinkage ratio = (BD-VBD) x 100/VBD (1) In the formula, BD is a bulk density of the non-crosslinked foamed polyethylene resin particles at 23°C and 0.1 MPa (under standard atmospheric pressure), and VBD is a bulk density of the non-crosslinked foamed polyethylene resin particles at 23°C under a reduced pressure of 0.002 MPa or less.

  所提供的非交联发泡聚乙烯树脂颗粒的体积密度 BD 为 10 g/L 或以上、100 g/L 或以下，是通过发泡含有抗静电剂的聚乙烯树脂颗粒获得的，抗静电剂的用量为 0.该非交联发泡聚乙烯树脂颗粒的收缩率为3%或以上，30%或以下，根据式(1)测定，其密度为0.920克/立方厘米或以上，0.940克/立方厘米以下。非交联发泡聚乙烯树脂颗粒可以简单地提供抗静电模塑非交联发泡聚乙烯树脂体，该体相对于模具尺寸的收缩率小，变形程度小，表面伸展性好。收缩率＝（BD-VBD）×100/VBD (1) 式中，BD 是非交联发泡聚乙烯树脂颗粒在 23℃和 0.1 兆帕（标准大气压下）时的体积密度，VBD 是非交联发泡聚乙烯树脂颗粒在 23℃、减压 0.002 兆帕或以下时的体积密度。
• LUBRICATING OIL COMPOSITION, AND SLIDING MECHANISM USING LUBRICATING OIL COMPOSITION
  申请人：Idemitsu Kosan Co., Ltd

  公开号：EP2826845A1

  公开（公告）日：2015-01-21

  Disclosed is a lubricating oil composition for low-friction sliding materials, which is used in a sliding mechanism where a DLC film containing hydrogen in an amount of from 5 atom% to 50 atom% is formed on at least one sliding surface. The lubricating oil composition contains, in the lubricant base oil therein and based on the total amount of the composition, (A) an organic zinc dithiophosphate in an amount of from 0.005% by mass to 0.12% by mass in terms of the phosphorus concentration therein, (B) an amine-based friction-reducing agent in an amount of from 0.05% by mass to 5.0% by mass, and (C) an alkaline earth metal salicylate-based detergent and/or an alkaline earth metal sulfonate-based detergent in an amount of from 0.05% by mass to 0.5% by mass in terms of the alkaline earth metal concentration therein, wherein the component (A) contains, based on the total amount of the composition, a zinc primary dialkyldithiophosphate in an amount of from 0.005% by mass to 0.05% by mass in terms of the phosphorus concentration therein.

  本发明公开了一种用于低摩擦滑动材料的润滑油组合物，该组合物用于在至少一个滑动表面上形成含氢量为 5 原子％至 50 原子％的 DLC 膜的滑动机构中。该润滑油组合物在其中的润滑油基础油中，根据组合物的总量，含有 (A) 有机二硫代磷酸锌，以其中的磷浓度计，含量为 0.005% （质量百分比）至 0.12% （质量百分比）；(B) 基于胺的减摩剂，含量为 0.05% （质量百分比）至 5.(C) 碱土金属水杨酸酯类洗涤剂和/或碱土金属磺酸盐类洗涤剂，以其中碱土金属的浓度计，其用量为 0.05% (质量) 至 0.5% (质量)，其中组分 (A) 含有以组合物总量计，以其中磷的浓度计，其用量为 0.005% (质量) 至 0.05% (质量)的伯基二烷基二硫代磷酸锌。
• LUBRICANT OIL COMPOSITION
  申请人：Idemitsu Kosan Co., Ltd

  公开号：EP3115444A1

  公开（公告）日：2017-01-11

  Provided is a lubricating oil composition favorable for reducing friction in a sliding mechanism equipped with a piston ring and a liner, in a device having the sliding mechanism. The lubricating oil composition contains a lubricant base oil, (1) a polymethacrylate and/or an olefin copolymer having a mass-average molecular weight of 100,000 to 600,000, and (2) an ester-type ashless friction modifier and/or an amine-type ashless friction modifier, and has a shear viscosity at 150°C of 2.3 mPa· or more and less than 3.7 mPa·s.

  本文提供了一种润滑油组合物，该组合物有利于在具有滑动机构的设备中减少装有活塞环和衬垫的滑动机构的摩擦。该润滑油组合物包含润滑油基础油、(1) 聚甲基丙烯酸酯和/或烯烃共聚物，其质量平均分子量为 100,000 至 600,000，以及 (2) 酯类无灰摩擦改进剂和/或胺类无灰摩擦改进剂，并且在 150°C 时的剪切粘度为 2.3 mPa- 或以上且小于 3.7 mPa-s。
• SLIDING MECHANISM WITH LUBRICATING OIL COMPOSITION
  申请人：Idemitsu Kosan Co., Ltd

  公开号：EP2826845B1

  公开（公告）日：2021-03-10