(3,4-dimethyl-phenyl)-[1]naphthyl-amine | 205986-28-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: (3,4-dimethyl-phenyl)-[1]naphthyl-amine
• 英文别名: N-(3,4-dimethylphenyl)naphthalen-1-amine
• CAS: 205986-28-3
• 化学式: C₁₈H₁₇N
• 分子量: 247.34
• InChiKey: NCCSHYMFRGUGQQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (3,4-dimethyl-phenyl)-[1]naphthyl-amine 在 碘 、 sulfur 作用下， 生成 9,10-dimethyl-12H-benzo[a]phenothiazine
  参考文献：
  名称：

  236.致癌性氮化合物的化学作用。第四部分 新的取代角苯并cr啶和二苯并cr啶

  摘要：

  DOI：

  10.1039/jr9500001146
• 作为产物：
  描述：

  tri(naphthalen-1-yl)bismuth 、 3,4-二甲基苯胺 在 copper diacetate 、 碘苯二乙酸 作用下， 生成 (3,4-dimethyl-phenyl)-[1]naphthyl-amine
  参考文献：
  名称：

  Triarylbismuthane - iodobenzene diacetate: One-pot system for copper-catalysed N-arylation under neutral conditions

  摘要：

  Triarylbismuthanes react with iodobenzene diacetate in dichloromethane under mild, neutral conditions to afford triarylbismuth diacetates, which can be isolated in good yields. The reagents can also be directly used in a one-pot copper-catalysed N-arylation of anilines to give near quantitative yields of the corresponding diarylamines, except in the case of the 2-methoxyphenylbismuth derivative. N-arylation with tris(2-methoxyphenyl)bismuth diacetate was quantitative only when the reaction was performed with the pure isolated reagent. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(98)00126-4

文献信息

• 144. The chemistry of carcinogenic nitrogen compounds. Part II. Further derivatives of 1 : 2- and 3 : 4-benzacridines
  作者：Ng. Ph. Buu-Hoï

  DOI：10.1039/jr9490000670

  日期：——
• 173. Carcinogenic nitrogen compounds. Part VI. Derivatives of 1 : 2- and 3 : 4-benzophenarsazines
  作者：Ng. Ph. Buu-Hoï、René Royer

  DOI：10.1039/jr9510000795

  日期：——
• 236. The chemistry of carcinogenic nitrogen compounds. Part IV. New substituted angular benzacridines and dibenzacridines
  作者：Ng. Ph. Buu-Hoï

  DOI：10.1039/jr9500001146

  日期：——
• Triarylbismuthane - iodobenzene diacetate: One-pot system for copper-catalysed N-arylation under neutral conditions
  作者：Sébastien Combes、Jean-Pierre Finet

  DOI：10.1016/s0040-4020(98)00126-4

  日期：1998.4

  Triarylbismuthanes react with iodobenzene diacetate in dichloromethane under mild, neutral conditions to afford triarylbismuth diacetates, which can be isolated in good yields. The reagents can also be directly used in a one-pot copper-catalysed N-arylation of anilines to give near quantitative yields of the corresponding diarylamines, except in the case of the 2-methoxyphenylbismuth derivative. N-arylation with tris(2-methoxyphenyl)bismuth diacetate was quantitative only when the reaction was performed with the pure isolated reagent. (C) 1998 Elsevier Science Ltd. All rights reserved.