trimethyl(2-(naphthalen-1-ylmethoxy)ethyl)silane | 1314564-46-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: trimethyl(2-(naphthalen-1-ylmethoxy)ethyl)silane
• 英文别名: Trimethyl-[2-(naphthalen-1-ylmethoxy)ethyl]silane
• CAS: 1314564-46-9
• 化学式: C₁₆H₂₂OSi
• 分子量: 258.436
• InChiKey: SQABFDIPMCSSLM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.69
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-(三甲硅基)乙醇 在 potassium phosphate 、 dichloro(cycloocta-1,5-diene)palladium (II) 、 1,1'-bis(diisopropylphosphino)ferrocene 、 potassium hydride 作用下， 以 四氢呋喃 、 水 、 叔丁醇 为溶剂， 反应 20.0h， 生成 trimethyl(2-(naphthalen-1-ylmethoxy)ethyl)silane
  参考文献：
  名称：

  Cross-Coupling of Mesylated Phenol Derivatives with Potassium Alkoxymethyltrifluoroborates

  摘要：

  Cross-coupling of mesylated phenol derivatives with various potassium alkoxymethyltrifluoroborates has been achieved. The corresponding aryl and heteroaryl alkoxymethyl compounds have been obtained with equal facility with both electron-rich and electron-poor substituents on the activated alcohol.

  DOI：

  10.1021/ol201469r

文献信息

• Cross-Coupling of Mesylated Phenol Derivatives with Potassium Alkoxymethyltrifluoroborates
  作者：Gary A. Molander、Floriane Beaumard

  DOI：10.1021/ol201469r

  日期：2011.8.5

  Cross-coupling of mesylated phenol derivatives with various potassium alkoxymethyltrifluoroborates has been achieved. The corresponding aryl and heteroaryl alkoxymethyl compounds have been obtained with equal facility with both electron-rich and electron-poor substituents on the activated alcohol.