2-[[(2R)-2-dodecanoyloxy-3-hexadecanoyloxypropoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 英文名称: 2-[[(2R)-2-dodecanoyloxy-3-hexadecanoyloxypropoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium
• 化学式: C36H73NO8P+
• 分子量: 678.9
• InChiKey: OVRJLLUJKRFEBG-UUWRZZSWSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  11.4
• 重原子数：
  46
• 可旋转键数：
  36
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  108
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• POLYMER-ENCAPSULATED DRUG PARTICLES
  申请人：GIE Medical, Inc.

  公开号：EP4106828A1

  公开（公告）日：2022-12-28
• Multi-Targeted Multi-Valent Ligand Drug Particles for the Treatment and Prevention of Diseases and Conditions
  申请人：Tran David T.

  公开号：US20200306384A1

  公开（公告）日：2020-10-01

  This disclosure relates to novel ligand-drug particles comprising at least one ligand specific for one or more cell surface receptor molecules for targeting the ligand-drug particles to a target cell. This disclosure also relates to pharmaceutical compositions comprising the particles herein and systems and methods for determining the ligand valency of the particles.