6-(1-Hydroxy-ethyl)-5,8-dihydro-naphthalene-1,4-diol | 86652-52-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 6-(1-Hydroxy-ethyl)-5,8-dihydro-naphthalene-1,4-diol
• 英文别名: 6-(1-Hydroxyethyl)-5,8-dihydronaphthalene-1,4-diol
• CAS: 86652-52-0
• 化学式: C₁₂H₁₄O₃
• 分子量: 206.241
• InChiKey: HZLFNHHTTZSTKL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  60.7
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  6-(1-Hydroxy-ethyl)-5,8-dihydro-naphthalene-1,4-diol 生成 (+/-)-5,8-dimethoxy-2,3-epoxy-2-(1'-hydroxyethyl)-1,2,3,4-tetrahydronaphthalene
  参考文献：
  名称：

  Synthesis in the Field of Natural Products of Biological Relevance

  摘要：

  AbstractThe chemical manipulation of the aminosugar, daunosamine, has resulted in the development of new interesting doxorubicin analogues, namely 4′‐epi‐ and 4′‐deoxydoxorubicin, whereas the total synthesis of new aglycones has provided new structural types of the anthracyclines. In the field of beta‐lactams, efforts aimed to the discovery of original anti‐infective compounds have led to the synthesis of novel “penem” derivatives starting from methyl penicillinate.

  DOI：

  10.1002/bscb.19820911207
• 作为产物：
  描述：

  2-(α-hydroxyethyl)-1,3-butadiene 、 对苯醌 以 苯 为溶剂， 以85%的产率得到6-(1-Hydroxy-ethyl)-5,8-dihydro-naphthalene-1,4-diol
  参考文献：
  名称：

  Nero, Stefano Del; Lombardi, Paolo, Gazzetta Chimica Italiana, 1983, vol. 113, # 1/2, p. 125 - 127

  摘要：

  DOI：

文献信息

• Synthesis in the Field of Natural Products of Biological Relevance
  作者：Federico Arcamone

  DOI：10.1002/bscb.19820911207

  日期：——

  AbstractThe chemical manipulation of the aminosugar, daunosamine, has resulted in the development of new interesting doxorubicin analogues, namely 4′‐epi‐ and 4′‐deoxydoxorubicin, whereas the total synthesis of new aglycones has provided new structural types of the anthracyclines. In the field of beta‐lactams, efforts aimed to the discovery of original anti‐infective compounds have led to the synthesis of novel “penem” derivatives starting from methyl penicillinate.
• Nero, Stefano Del; Lombardi, Paolo, Gazzetta Chimica Italiana, 1983, vol. 113, # 1/2, p. 125 - 127
  作者：Nero, Stefano Del、Lombardi, Paolo

  DOI：——

  日期：——