N-氨基-N'-1-辛基胍 | 66002-80-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: N-氨基-N'-1-辛基胍
• 英文名称: N-Amino-N'-1-octylguanidine
• 英文别名: 1-amino-2-octylguanidine
• CAS: 66002-80-0
• 化学式: C₉H₂₂N₄
• 分子量: 186.3
• InChiKey: MDHUTKMSNDEISD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  76.4
• 氢给体数：
  3
• 氢受体数：
  2

文献信息

• Compositions for in-situ active compound assembly
  申请人：SCRIPPS CLINIC AND RESEARCH FOUNDATION

  公开号：EP0603160A2

  公开（公告）日：1994-06-22

  A composition for chemically treating a target condition, existing at a microenvironment localized within an environment, with an active compound, the composition comprising precursor components which can conjugate covalently to form the active compound in situ, and for which the covalent conjugation is more favourable at the microenvironment of the target condition than in the surrounding environment. Disclosed examples include biologically-active compounds which are preferentially formed in the microenvironment of tumour cells.

  一种用于用活性化合物化学治疗存在于环境局部微环境中的目标病症的组合物，该组合物包含可共价结合以在原位形成活性化合物的前体成分，对于这些前体成分，共价结合在目标病症的微环境中比在周围环境中更有利。已公开的例子包括在肿瘤细胞的微环境中优先形成的生物活性化合物。
• Composition comprising decanal or as active ingredients for preventing hair loss or stimulating hair growth
  申请人：INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY

  公开号：US10617612B2

  公开（公告）日：2020-04-14

  A composition for preventing hair loss or promoting hair growth comprising Decanal or pharmaceutically acceptable salt thereof as an active ingredient is provided. In particular, the composition relates to a quasi-drug, a cosmetic composition, a health functional food composition, and a pharmaceutical composition for preventing hair loss or promoting hair growth, which exhibits an excellent and stable effect on hair growth and hair growth, even while comprising a natural compound which has no side effect even in long-term administration in a chronic disease as an active ingredient.

  本发明提供了一种预防脱发或促进生发的组合物，其活性成分包括癸醛或其药学上可接受的盐。特别是，该组合物涉及一种准药物、一种化妆品组合物、一种保健功能食品组合物，以及一种用于防止脱发或促进头发生长的药物组合物，该组合物对头发生长和毛发生长具有卓越而稳定的效果，同时还包含一种即使在慢性疾病中长期用药也不会产生副作用的天然化合物作为活性成分。
• $i(IN SITU) ACTIVE COMPOUND ASSEMBLY
  申请人：SCRIPPS CLINIC AND RESEARCH FOUNDATION

  公开号：EP0312543A1

  公开（公告）日：1989-04-26
• EP0312543A4
  申请人：——

  公开号：EP0312543A4

  公开（公告）日：1990-12-27
• COMPOSITION COMPRISING DECANAL OR AS ACTIVE INGREDIENTS FOR PREVENTING HAIR LOSS OR STIMULATING HAIR GROWTH
  申请人：INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY

  公开号：US20180104162A1

  公开（公告）日：2018-04-19

  A composition for preventing hair loss or promoting hair growth comprising Decanal or pharmaceutically acceptable salt thereof as an active ingredient is provided. In particular, the composition relates to a quasi-drug, a cosmetic composition, a health functional food composition, and a pharmaceutical composition for preventing hair loss or promoting hair growth, which exhibits an excellent and stable effect on hair growth and hair growth, even while comprising a natural compound which has no side effect even in long-term administration in a chronic disease as an active ingredient.