imidazolium tetrafluoroborate | 112725-76-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: imidazolium tetrafluoroborate
• 英文别名: Imidazolium tetrafluoroborate；1H-imidazol-3-ium;tetrafluoroborate
• CAS: 112725-76-5
• 化学式: BF₄*C₃H₅N₂
• 分子量: 155.891
• InChiKey: JUOVGTNBPZKSCY-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  0.36
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  29
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  咪唑 、 tetrafluoroboric acid 以 甲醇 为溶剂， 生成 imidazolium tetrafluoroborate
  参考文献：
  名称：

  Ferroelectric order in highly disordered molecular-ionic crystals

  摘要：

  The ordering of the anionic sublattice at the coexisting high orientational disorder of the cationic sublattice produces spontaneous polarization in imidazolium tetrafluoroborate [C3N2H5](+)[BF4](-). This ferroelectric crystal exhibits the Curie point at 297.0 K and undergoes two other polymorphic phase transitions at 213.6 and 187.8 K. In spite of its pentagonal ring the dynamically disordered polar cation is localized at a special position on the threefold axis of the highly symmetrical rhombohedral unit cell. Thus it does not contribute immediately to the spontaneous polarization which originates predominantly from the behavior of the distorted tetrahedral fluoroborate anion.

  DOI：

  10.1103/physrevb.69.132102

文献信息

• Activators for oligonucleotide synthesis
  申请人：——

  公开号：US20030191304A1

  公开（公告）日：2003-10-09

  The present invention relates to improved methods for the preparation of nucleoside phosphoramidites and oligonucleotides. In one aspect, the methods of the invention are used to prepare phosphitylating reagents using pyridinium salts as activators. In a further aspect, the methods of the invention are used to prepare internucleoside linkages using activators which include at least one pyridinium salt and at least one substituted imidazole. In a further aspect, methods are provided preparation of internucleoside linkages between nucleosides having 2′-substituents using imidazolium or benzimidazolium salts as an activator. In a further aspect, methods are provided preparation of internucleoside linkages between nucleosides having bioreversible protecting group that confers enhanced chemical and biophysical properties, without exocyclic amine protection, using imidazolium or benzimidazolium salts as an activator.

  本发明涉及改进的核苷酸磷酰胺和寡核苷酸制备方法。在一个方面，本发明的方法用于使用吡啶盐作为活化剂制备磷酸化试剂。在进一步的方面，本发明的方法用于使用至少一种吡啶盐和至少一种取代咪唑作为活化剂制备核苷酸间连接。在另一个方面，提供了一种方法，用于使用咪唑盐或苯并咪唑盐作为活化剂，制备具有2'-取代基的核苷酸之间的核苷酸间连接。在另一个方面，提供了一种方法，用于使用咪唑盐或苯并咪唑盐作为活化剂，在不进行外环胺保护的情况下，制备具有生物可逆保护基的核苷酸之间的核苷酸间连接，从而使其具有增强的化学和生物物理性质。