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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡啶及其衍生物

    吡啶及其衍生物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]cyclohex-3-ene-1-carboxamide —— C21H20FN3O2
    4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]cyclohex-3-ene-1-carboxamide
    —— 3-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}-3-oxopropanenitrile —— C22H20F2N4O2
    3-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}-3-oxopropanenitrile
    —— 4-[2-fluoro-5-(propan-2-yloxy)phenyl]-2-[1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl]-1H-pyrrolo[2,3-b]pyridine —— C22H24FN3O3S
    4-[2-fluoro-5-(propan-2-yloxy)phenyl]-2-[1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl]-1H-pyrrolo[2,3-b]pyridine
    —— 4-(4-fluoro-2-methoxyphenyl)-2-[2-(methylsulfonyl)-1,2,3,3a,4,6a-hexahydrocyclopenta[c]pyrrol-5-yl]-1H-pyrrolo[2,3-b]pyridine —— C22H22FN3O3S
    4-(4-fluoro-2-methoxyphenyl)-2-[2-(methylsulfonyl)-1,2,3,3a,4,6a-hexahydrocyclopenta[c]pyrrol-5-yl]-1H-pyrrolo[2,3-b]pyridine
    —— tert-butyl 3-[4-[3-chloro-6-(oxan-4-ylmethylamino)pyridin-2-yl]-5-(4-methylphenyl)sulfonyl-1H-pyrrolo[2,3-b]pyridin-2-yl]pyrrolidine-1-carboxylate —— C34H40ClN5O5S
    tert-butyl 3-[4-[3-chloro-6-(oxan-4-ylmethylamino)pyridin-2-yl]-5-(4-methylphenyl)sulfonyl-1H-pyrrolo[2,3-b]pyridin-2-yl]pyrrolidine-1-carboxylate
    —— 4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-N-[2-(3-hydroxypiperidin-1-yl)ethyl]-3,6-dihydropyridine-1(2H)-carboxamide —— C27H32FN5O3
    4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-N-[2-(3-hydroxypiperidin-1-yl)ethyl]-3,6-dihydropyridine-1(2H)-carboxamide
    —— N-(2-{2-[1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-4-yl}phenyl)methanesulfonamide —— C20H22N4O4S2
    N-(2-{2-[1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl]-1H-pyrrolo[2,3-b]pyridin-4-yl}phenyl)methanesulfonamide
    —— 4-(4,5-difluoro-2-methoxyphenyl)-2-[2-(methylsulfonyl)-1,2,3,3a,4,6a-hexahydrocyclopenta[c]pyrrol-5-yl]-1H-pyrrolo[2,3-b]pyridine —— C22H21F2N3O3S
    4-(4,5-difluoro-2-methoxyphenyl)-2-[2-(methylsulfonyl)-1,2,3,3a,4,6a-hexahydrocyclopenta[c]pyrrol-5-yl]-1H-pyrrolo[2,3-b]pyridine
    —— 4-fluoro-3-{2-[1-(methylsulfonyl)piperidin-4-yl]-1H-pyrrolo[2,3-b]pyridin-4-yl}-N-(pyridin-4-ylmethyl)aniline —— C25H26FN5O2S
    4-fluoro-3-{2-[1-(methylsulfonyl)piperidin-4-yl]-1H-pyrrolo[2,3-b]pyridin-4-yl}-N-(pyridin-4-ylmethyl)aniline
    —— 2-{3-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-2,5-dihydro-1H-pyrrol-1-yl}-1-(3-hydroxyazetidin-1-yl)ethanone —— C23H23FN4O3
    2-{3-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-2,5-dihydro-1H-pyrrol-1-yl}-1-(3-hydroxyazetidin-1-yl)ethanone
    —— US9796708, Example 960 —— C24H24FN3O4
    US9796708, Example 960
    —— US9796708, Example 744 —— C24H27FN4O4S
    US9796708, Example 744
    —— 4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-N,N-dimethylcyclohex-3-ene-1-carboxamide —— C23H24FN3O2
    4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-N,N-dimethylcyclohex-3-ene-1-carboxamide
    —— 2-[1-(1-tert-butylpyrrolidin-3-yl)pyrrolidin-3-yl]-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine —— C26H33FN4O
    2-[1-(1-tert-butylpyrrolidin-3-yl)pyrrolidin-3-yl]-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine
    —— 2-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}-1-(3-hydroxypyrrolidin-1-yl)ethanone —— C25H27FN4O3
    2-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}-1-(3-hydroxypyrrolidin-1-yl)ethanone
    —— 2-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}-1-[(3R)-3-hydroxypyrrolidin-1-yl]ethanone —— C25H27FN4O3
    2-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}-1-[(3R)-3-hydroxypyrrolidin-1-yl]ethanone
    —— 4-[5-[(3,5-difluorophenyl)methoxy]-2-fluorophenyl]-2-(2-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine —— C26H22F3N3O
    4-[5-[(3,5-difluorophenyl)methoxy]-2-fluorophenyl]-2-(2-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine
    —— US9796708, Example 342 —— C25H29FN6O2
    US9796708, Example 342
    —— 2-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}-N-(methylsulfonyl)acetamide —— C22H25FN4O4S
    2-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}-N-(methylsulfonyl)acetamide
    —— 2-{3-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]pyrrolidin-1-yl}-N,N-dimethylacetamide —— C22H25FN4O2
    2-{3-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]pyrrolidin-1-yl}-N,N-dimethylacetamide
    —— 2-{4-[4-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}-N-methylacetamide —— C22H26N4O2
    2-{4-[4-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}-N-methylacetamide
    —— 2-[1-(2,3-dihydroxypropyl)-1,2,3,6-tetrahydropyridin-4-yl]-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide —— C23H25FN4O4
    2-[1-(2,3-dihydroxypropyl)-1,2,3,6-tetrahydropyridin-4-yl]-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide
    —— 2-{4-[4-(5-fluoro-2-methoxyphenyl)-5-methoxy-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}-1-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]ethanone —— C27H31FN4O4
    2-{4-[4-(5-fluoro-2-methoxyphenyl)-5-methoxy-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}-1-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]ethanone
    —— 4-(5-fluoro-2-methoxyphenyl)-2-[1-(methylsulfonyl)-2,3,6,7-tetrahydro-1H-azepin-4-yl]-1H-pyrrolo[2,3-b]pyridine —— C21H22FN3O3S
    4-(5-fluoro-2-methoxyphenyl)-2-[1-(methylsulfonyl)-2,3,6,7-tetrahydro-1H-azepin-4-yl]-1H-pyrrolo[2,3-b]pyridine
    —— US9796708, Example 617 —— C23H26N4O3
    US9796708, Example 617
    —— 1-{4-[4-(2,3-difluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}-2-hydroxyethanone —— C20H17F2N3O2
    1-{4-[4-(2,3-difluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}-2-hydroxyethanone
    —— (6S)-4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-6-methyl-3,6-dihydro-2H-pyridine-1-sulfinate —— C20H19FN3O3S-
    (6S)-4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-6-methyl-3,6-dihydro-2H-pyridine-1-sulfinate
    —— 4-(5-fluoro-2-methoxyphenyl)-2-(1-hydroxy-3,6-dihydro-2H-pyridin-5-yl)-1H-pyrrolo[2,3-b]pyridine —— C19H18FN3O2
    4-(5-fluoro-2-methoxyphenyl)-2-(1-hydroxy-3,6-dihydro-2H-pyridin-5-yl)-1H-pyrrolo[2,3-b]pyridine
    —— tert-butyl 3-[4-[2-chloro-5-(oxan-3-ylmethylamino)phenyl]-1H-pyrrolo[2,3-b]pyridin-2-yl]-2,5-dihydropyrrole-1-carboxylate —— C28H33ClN4O3
    tert-butyl 3-[4-[2-chloro-5-(oxan-3-ylmethylamino)phenyl]-1H-pyrrolo[2,3-b]pyridin-2-yl]-2,5-dihydropyrrole-1-carboxylate
    —— 4-(5-fluoro-2-methoxyphenyl)-2-(1-{[2-(2-methoxyethoxy)ethyl]sulfonyl}-1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine —— C24H28FN3O5S
    4-(5-fluoro-2-methoxyphenyl)-2-(1-{[2-(2-methoxyethoxy)ethyl]sulfonyl}-1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine
    —— 2-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}-N-methyl-2-oxoethanesulfonamide —— C22H23FN4O4S
    2-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}-N-methyl-2-oxoethanesulfonamide
    —— 5-({4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one —— C22H23FN6O2
    5-({4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
    —— 4-(5-fluoro-2-methoxyphenyl)-2-[(6R)-6-methyl-1,2,3,6-tetrahydropyridin-4-yl]-1H-pyrrolo[2,3-b]pyridine —— C20H20FN3O
    4-(5-fluoro-2-methoxyphenyl)-2-[(6R)-6-methyl-1,2,3,6-tetrahydropyridin-4-yl]-1H-pyrrolo[2,3-b]pyridine
    —— 2-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}-1-(3-hydroxy-3-methylazetidin-1-yl)ethanone —— C25H27FN4O3
    2-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}-1-(3-hydroxy-3-methylazetidin-1-yl)ethanone
    —— 4-(5-fluoro-2-methoxyphenyl)-2-{1-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperidin-4-yl}-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile —— C25H26FN5O3
    4-(5-fluoro-2-methoxyphenyl)-2-{1-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperidin-4-yl}-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile
    —— [(2S)-4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-2-(hydroxymethyl)-2,5-dihydropyrrol-1-yl]sulfonylcarbamic acid —— C20H19FN4O6S
    [(2S)-4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-2-(hydroxymethyl)-2,5-dihydropyrrol-1-yl]sulfonylcarbamic acid
    —— 4-(2-ethylphenyl)-2-[1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl]-1H-pyrrolo[2,3-b]pyridine —— C21H23N3O2S
    4-(2-ethylphenyl)-2-[1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl]-1H-pyrrolo[2,3-b]pyridine
    —— ethyl 1-({4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}carbonyl)-4-hydroxypiperidine-4-carboxylate —— C28H31FN4O5
    ethyl 1-({4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}carbonyl)-4-hydroxypiperidine-4-carboxylate
    —— [4-[1-(Benzenesulfonyl)-4-(5-fluoro-2-methoxyphenyl)pyrrolo[2,3-b]pyridin-2-yl]cyclohex-3-en-1-yl]carbamic acid —— C27H24FN3O5S
    [4-[1-(Benzenesulfonyl)-4-(5-fluoro-2-methoxyphenyl)pyrrolo[2,3-b]pyridin-2-yl]cyclohex-3-en-1-yl]carbamic acid
    —— 4-(4,5-difluoro-2-methoxyphenyl)-2-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine —— C20H19F2N3O
    4-(4,5-difluoro-2-methoxyphenyl)-2-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine
    —— 2-(1-benzyl-3,4-dihydro-2H-pyridin-4-yl)-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine —— C26H24FN3O
    2-(1-benzyl-3,4-dihydro-2H-pyridin-4-yl)-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine
    —— 2-{3-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-9-azabicyclo[3.3.1]non-2-en-9-yl}-N,N-dimethylacetamide —— C26H29FN4O2
    2-{3-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-9-azabicyclo[3.3.1]non-2-en-9-yl}-N,N-dimethylacetamide
    —— N-(cyclopropylsulfonyl)-4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]cyclohex-3-ene-1-carboxamide —— C24H24FN3O4S
    N-(cyclopropylsulfonyl)-4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]cyclohex-3-ene-1-carboxamide
    —— 2-[1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl]-4-(2,3,4-trifluorophenyl)-1H-pyrrolo[2,3-b]pyridine —— C19H16F3N3O2S
    2-[1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl]-4-(2,3,4-trifluorophenyl)-1H-pyrrolo[2,3-b]pyridine
    —— N-(2,5-difluorobenzyl)-4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]cyclohex-3-ene-1-carboxamide —— C28H24F3N3O2
    N-(2,5-difluorobenzyl)-4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]cyclohex-3-ene-1-carboxamide
    —— 4-(3-fluoro-2-methoxyphenyl)-2-[1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl]-1H-pyrrolo[2,3-b]pyridine —— C20H20FN3O3S
    4-(3-fluoro-2-methoxyphenyl)-2-[1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl]-1H-pyrrolo[2,3-b]pyridine
    —— US9796708, Example 840 —— C21H23FN4O3S
    US9796708, Example 840
    —— US9796708, Example 870 —— C22H19FN4O3
    US9796708, Example 870
    —— US9796708, Example 661 —— C21H22FN3O5S2
    US9796708, Example 661
    —— N-[4-[2-(1-methylsulfonyl-3,4-dihydro-2H-pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]phenyl]methanesulfonamide —— C20H22N4O4S2
    N-[4-[2-(1-methylsulfonyl-3,4-dihydro-2H-pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]phenyl]methanesulfonamide