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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡啶及其衍生物

    吡啶及其衍生物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-[5-(1,3-Benzothiazol-2-ylmethoxy)-1-[[4-[6-(trifluoromethyl)pyridin-3-yl]phenyl]methyl]benzimidazol-2-yl]cyclohexane-1-carboxylic acid —— C35H29F3N4O3S
    2-[5-(1,3-Benzothiazol-2-ylmethoxy)-1-[[4-[6-(trifluoromethyl)pyridin-3-yl]phenyl]methyl]benzimidazol-2-yl]cyclohexane-1-carboxylic acid
    —— 3-(3-Chlorophenyl)-2-(difluoromethoxy)-5-methanidylpyridine;ZINC;hydrobromide —— C13H10BrClF2NOZn-
    3-(3-Chlorophenyl)-2-(difluoromethoxy)-5-methanidylpyridine;ZINC;hydrobromide
    —— 2-(1-{[5-(3-chlorophenyl)-6-methoxypyridin-3-yl]methyl}-1H-1,2,4-triazol-3-yl)propan-2-ol —— C18H19ClN4O2
    2-(1-{[5-(3-chlorophenyl)-6-methoxypyridin-3-yl]methyl}-1H-1,2,4-triazol-3-yl)propan-2-ol
    —— (1-{[6-(difluoromethoxy)-5-[2-(difluoromethoxy)pyridin-4-yl]pyridin-3-yl]methyl}-1H-1,2,4-triazol-3-yl)methanol —— C16H13F4N5O3
    (1-{[6-(difluoromethoxy)-5-[2-(difluoromethoxy)pyridin-4-yl]pyridin-3-yl]methyl}-1H-1,2,4-triazol-3-yl)methanol
    —— 4-{[5-(3-chlorophenyl)-6-methoxypyridin-3-yl]methyl}-N-(oxetan-3-yl)benzamide —— C23H21ClN2O3
    4-{[5-(3-chlorophenyl)-6-methoxypyridin-3-yl]methyl}-N-(oxetan-3-yl)benzamide
    —— 3-[2-[[(1S)-1-[5-(4-fluoro-3-methylphenyl)pyridin-2-yl]ethyl]amino]pyrimidin-4-yl]-4-[(1R)-1-[(2-methylpropan-2-yl)oxy]ethyl]-1,3-oxazolidin-2-one —— C27H32FN5O3
    3-[2-[[(1S)-1-[5-(4-fluoro-3-methylphenyl)pyridin-2-yl]ethyl]amino]pyrimidin-4-yl]-4-[(1R)-1-[(2-methylpropan-2-yl)oxy]ethyl]-1,3-oxazolidin-2-one
    —— (3-(2H-1,2,3-triazol-2-yl)pyridin-2-yl)((1S,4R,6R)-6-((5-(trifluoromethyl)pyridin-2-yl)oxy)-2-azabicyclo[2,2,1]heptan-2-yl)methanone —— C20H17F3N6O2
    (3-(2H-1,2,3-triazol-2-yl)pyridin-2-yl)((1S,4R,6R)-6-((5-(trifluoromethyl)pyridin-2-yl)oxy)-2-azabicyclo[2,2,1]heptan-2-yl)methanone
    —— 1-{[5-(3-chlorophenyl)-6-methoxypyridin-3-yl]methyl}-1H-1,2,4-triazole-3-carboxamide —— C16H14ClN5O2
    1-{[5-(3-chlorophenyl)-6-methoxypyridin-3-yl]methyl}-1H-1,2,4-triazole-3-carboxamide
    —— (4R)-3-[2-[[(1S)-1-[5-(4-fluoro-3-methylphenyl)pyridin-2-yl]ethyl]amino]pyrimidin-4-yl]-4-[(1R)-1-[(2-methylpropan-2-yl)oxy]ethyl]-1,3-oxazolidin-2-one —— C27H32FN5O3
    (4R)-3-[2-[[(1S)-1-[5-(4-fluoro-3-methylphenyl)pyridin-2-yl]ethyl]amino]pyrimidin-4-yl]-4-[(1R)-1-[(2-methylpropan-2-yl)oxy]ethyl]-1,3-oxazolidin-2-one
    —— 4-[[5-(3-Chlorophenyl)-6-methoxypyridin-3-yl]methyl]benzamide —— C20H17ClN2O2
    4-[[5-(3-Chlorophenyl)-6-methoxypyridin-3-yl]methyl]benzamide
    —— (7Z)-7-benzylidene-3-bromo-5,6-dihydrocyclopenta[b]pyridine —— C15H12BrN
    (7Z)-7-benzylidene-3-bromo-5,6-dihydrocyclopenta[b]pyridine
    —— US9650358, Example 84 —— C34H33ClFN5
    US9650358, Example 84
    —— US9650358, Example 260 —— C21H20ClN7O2
    US9650358, Example 260
    —— 4-amino-6-(2-carboxy-4-chloro-3-fluorophenyl)-3-chloropicolinic acid —— C13H7Cl2FN2O4
    4-amino-6-(2-carboxy-4-chloro-3-fluorophenyl)-3-chloropicolinic acid
    —— US9650358, Example 164 —— C27H28ClN7O
    US9650358, Example 164
    —— 4-[(1S)-1-fluoroethyl]-3-[5-fluoro-2-[[(1S)-1-[5-[3-(trifluoromethyl)phenyl]pyridin-2-yl]ethyl]amino]pyrimidin-4-yl]-1,3-oxazolidin-2-one —— C23H20F5N5O2
    4-[(1S)-1-fluoroethyl]-3-[5-fluoro-2-[[(1S)-1-[5-[3-(trifluoromethyl)phenyl]pyridin-2-yl]ethyl]amino]pyrimidin-4-yl]-1,3-oxazolidin-2-one
    —— (4R)-3-[2-[[(1S)-1-[2,5-difluoro-4-[2-(trifluoromethyl)pyridin-4-yl]phenyl]ethyl]amino]pyrimidin-4-yl]-4-[(1S)-1-fluoroethyl]-1,3-oxazolidin-2-one —— C23H19F6N5O2
    (4R)-3-[2-[[(1S)-1-[2,5-difluoro-4-[2-(trifluoromethyl)pyridin-4-yl]phenyl]ethyl]amino]pyrimidin-4-yl]-4-[(1S)-1-fluoroethyl]-1,3-oxazolidin-2-one
    —— 4-amino-3-chloro-6-(2,4-dichloro-3-fluorophenyl)-5-fluoropicolinic acid —— C12H5Cl3F2N2O2
    4-amino-3-chloro-6-(2,4-dichloro-3-fluorophenyl)-5-fluoropicolinic acid
    —— US9650358, Example 241 —— C36H39ClFN5OS
    US9650358, Example 241
    —— 1-(4-{[5-(3-chlorophenyl)-6-methoxypyridin-3-yl]methyl}phenyl)-3-(oxetan-3-yl)urea —— C23H22ClN3O3
    1-(4-{[5-(3-chlorophenyl)-6-methoxypyridin-3-yl]methyl}phenyl)-3-(oxetan-3-yl)urea
    —— (3R)-N-(5-chloro-4-{1-[3-(3-fluorophenyl)propyl]-1H-benzotriazol-6-yl}pyridin-2-yl)piperidine-3-carboxamide —— C26H26ClFN6O
    (3R)-N-(5-chloro-4-{1-[3-(3-fluorophenyl)propyl]-1H-benzotriazol-6-yl}pyridin-2-yl)piperidine-3-carboxamide
    —— 5-(chloro(4-fluorophenyl)methyl)-3-(3-chlorophenyl)-2-methoxypyridine —— C19H14Cl2FNO
    5-(chloro(4-fluorophenyl)methyl)-3-(3-chlorophenyl)-2-methoxypyridine
    —— 2-(5-{[5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl]methyl}pyridin-2-yl)propan-2-ol —— C21H19ClF2N2O2
    2-(5-{[5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl]methyl}pyridin-2-yl)propan-2-ol
    —— (1S,2R)-2-[5-(quinolin-2-ylmethoxy)-1-[[4-[6-(trifluoromethyl)pyridin-3-yl]phenyl]methyl]benzimidazol-2-yl]cyclohexane-1-carboxylic acid —— C37H31F3N4O3
    (1S,2R)-2-[5-(quinolin-2-ylmethoxy)-1-[[4-[6-(trifluoromethyl)pyridin-3-yl]phenyl]methyl]benzimidazol-2-yl]cyclohexane-1-carboxylic acid
    —— 3-(3-Chlorophenyl)-2-propan-2-yloxy-5-(1,2,4-triazol-1-ylmethyl)pyridine —— C17H17ClN4O
    3-(3-Chlorophenyl)-2-propan-2-yloxy-5-(1,2,4-triazol-1-ylmethyl)pyridine
    —— 1-[5-(4-Fluoro-3-methylphenyl)pyridin-2-yl]ethylcarbamic acid —— C15H15FN2O2
    1-[5-(4-Fluoro-3-methylphenyl)pyridin-2-yl]ethylcarbamic acid
    —— 1-[[5-(3-Chlorophenyl)-6-methoxypyridin-3-yl]methyl]pyridin-2-one —— C18H15ClN2O2
    1-[[5-(3-Chlorophenyl)-6-methoxypyridin-3-yl]methyl]pyridin-2-one
    —— 4-[(1S)-1-fluoroethyl]-3-[2-[[(1S)-1-[1-[6-(trifluoromethyl)pyridin-3-yl]pyrazol-3-yl]ethyl]amino]pyrimidin-4-yl]-1,3-oxazolidin-2-one —— C20H19F4N7O2
    4-[(1S)-1-fluoroethyl]-3-[2-[[(1S)-1-[1-[6-(trifluoromethyl)pyridin-3-yl]pyrazol-3-yl]ethyl]amino]pyrimidin-4-yl]-1,3-oxazolidin-2-one
    —— N-{5-chloro-4-[1-(3-fluorobenzyl)-1H-benzimidazol-6-yl]pyridin-2-yl}cyclohexane-1,3-diamine —— C25H25ClFN5
    N-{5-chloro-4-[1-(3-fluorobenzyl)-1H-benzimidazol-6-yl]pyridin-2-yl}cyclohexane-1,3-diamine
    —— [2-chloro-3-(trifluoromethyl)phenyl]-[(1S,8R)-5-[4-(difluoromethoxy)pyridin-2-yl]-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]methanone;(2,3-dichloro-4-fluorophenyl)-[(1S,8R)-5-[4-(difluoromethoxy)pyridin-2-yl]-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]methanone;(2,3-dichlorophenyl)-[(1S,8R)-5-(3-fluoro-4-methoxypyridin-2-yl)-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]methanone —— C61H45Cl5F9N15O9
    [2-chloro-3-(trifluoromethyl)phenyl]-[(1S,8R)-5-[4-(difluoromethoxy)pyridin-2-yl]-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]methanone;(2,3-dichloro-4-fluorophenyl)-[(1S,8R)-5-[4-(difluoromethoxy)pyridin-2-yl]-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]methanone;(2,3-dichlorophenyl)-[(1S,8R)-5-(3-fluoro-4-methoxypyridin-2-yl)-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]methanone
    —— 5-({6-[3-(difluoromethoxy)phenyl]-5-ethoxypyrazin-2-yl}methyl)pyridine-2-carboxamide —— C20H18F2N4O3
    5-({6-[3-(difluoromethoxy)phenyl]-5-ethoxypyrazin-2-yl}methyl)pyridine-2-carboxamide
    —— 2-(Difluoromethoxy)-3-(3-methoxyphenyl)-5-(1,2,4-triazol-1-ylmethyl)pyridine —— C16H14F2N4O2
    2-(Difluoromethoxy)-3-(3-methoxyphenyl)-5-(1,2,4-triazol-1-ylmethyl)pyridine
    —— [2-fluoro-3-(trifluoromethyl)phenyl]-[(1S,8R)-5-pyridin-2-yl-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]methanone —— C20H15F4N5O2
    [2-fluoro-3-(trifluoromethyl)phenyl]-[(1S,8R)-5-pyridin-2-yl-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]methanone
    —— US9650358, Example 193 —— C24H20ClFN4O2
    US9650358, Example 193
    —— 5-[[5-[3-(Difluoromethoxy)phenyl]-6-methoxypyridin-3-yl]methyl]pyrimidine —— C18H15F2N3O2
    5-[[5-[3-(Difluoromethoxy)phenyl]-6-methoxypyridin-3-yl]methyl]pyrimidine
    —— (4R)-3-[2-[[(1S)-1-[3-fluoro-5-[2-(trifluoromethyl)pyridin-4-yl]pyridin-2-yl]ethyl]amino]pyrimidin-4-yl]-4-[(1R)-1-[(2-methylpropan-2-yl)oxy]ethyl]-1,3-oxazolidin-2-one —— C26H28F4N6O3
    (4R)-3-[2-[[(1S)-1-[3-fluoro-5-[2-(trifluoromethyl)pyridin-4-yl]pyridin-2-yl]ethyl]amino]pyrimidin-4-yl]-4-[(1R)-1-[(2-methylpropan-2-yl)oxy]ethyl]-1,3-oxazolidin-2-one
    —— [3-fluoro-2-(trifluoromethyl)pyridin-4-yl]-[(1S,8R)-5-pyridin-2-yl-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]methanone —— C19H14F4N6O2
    [3-fluoro-2-(trifluoromethyl)pyridin-4-yl]-[(1S,8R)-5-pyridin-2-yl-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]methanone
    —— 3-[2-[[(1S)-1-[2,5-difluoro-4-[2-(trifluoromethyl)pyridin-4-yl]phenyl]ethyl]amino]pyrimidin-4-yl]-4-[(1S)-1-fluoroethyl]-1,3-oxazolidin-2-one —— C23H19F6N5O2
    3-[2-[[(1S)-1-[2,5-difluoro-4-[2-(trifluoromethyl)pyridin-4-yl]phenyl]ethyl]amino]pyrimidin-4-yl]-4-[(1S)-1-fluoroethyl]-1,3-oxazolidin-2-one
    —— 3-(3-Chlorophenyl)-2-(difluoromethoxy)-5-methylpyridine —— C13H10ClF2NO
    3-(3-Chlorophenyl)-2-(difluoromethoxy)-5-methylpyridine
    —— US9650358, Example 125 —— C25H25ClFN5
    US9650358, Example 125
    —— (S)-1-(2'-(trifluoromethyl)-[3,4'-bipyridin]-6-yl)ethanamine —— C13H12F3N3
    (S)-1-(2'-(trifluoromethyl)-[3,4'-bipyridin]-6-yl)ethanamine
    —— ethyl 1-{[5-(3-chlorophenyl)-6-methoxypyridin-3-yl]methyl}-1H-pyrazole-4-carboxylate —— C19H18ClN3O3
    ethyl 1-{[5-(3-chlorophenyl)-6-methoxypyridin-3-yl]methyl}-1H-pyrazole-4-carboxylate
    —— [2-fluoro-3-(trifluoromethyl)phenyl]-[(1S,8R)-5-(6-methylpyridin-2-yl)-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]methanone —— C21H17F4N5O2
    [2-fluoro-3-(trifluoromethyl)phenyl]-[(1S,8R)-5-(6-methylpyridin-2-yl)-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]methanone
    —— 4-N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-4-N-(pyridin-4-ylmethyl)cyclohexane-1,4-diamine —— C31H30ClFN6
    4-N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-4-N-(pyridin-4-ylmethyl)cyclohexane-1,4-diamine
    —— N-[2-[5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl]ethyl]-1H-1,2,4-triazol-5-amine —— C16H14ClF2N5O
    N-[2-[5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl]ethyl]-1H-1,2,4-triazol-5-amine
    —— (4R)-3-[2-[[(1S)-1-[6-(4-fluoro-3-methylphenyl)pyridin-3-yl]ethyl]amino]pyrimidin-4-yl]-4-[(1R)-1-[(2-methylpropan-2-yl)oxy]ethyl]-1,3-oxazolidin-2-one —— C27H32FN5O3
    (4R)-3-[2-[[(1S)-1-[6-(4-fluoro-3-methylphenyl)pyridin-3-yl]ethyl]amino]pyrimidin-4-yl]-4-[(1R)-1-[(2-methylpropan-2-yl)oxy]ethyl]-1,3-oxazolidin-2-one
    —— [2-chloro-3-(trifluoromethyl)phenyl]-[(1S,8R)-5-pyridin-2-yl-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]methanone —— C20H15ClF3N5O2
    [2-chloro-3-(trifluoromethyl)phenyl]-[(1S,8R)-5-pyridin-2-yl-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]methanone
    —— 2-[(5-chloro-4-{1-[(5-fluoropyridin-3-yl)methyl]-1H-benzimidazol-6-yl}pyridin-2-yl)amino]ethanol —— C20H17ClFN5O
    2-[(5-chloro-4-{1-[(5-fluoropyridin-3-yl)methyl]-1H-benzimidazol-6-yl}pyridin-2-yl)amino]ethanol
    —— US9650358, Example 184 —— C22H18ClFN4O3S
    US9650358, Example 184
    —— ethyl-[[4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]cyclohex-3-en-1-yl]sulfamoyl]carbamic acid —— C23H25FN4O5S
    ethyl-[[4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]cyclohex-3-en-1-yl]sulfamoyl]carbamic acid