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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡啶及其衍生物

    吡啶及其衍生物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— US9650358, Example 194 —— C27H23ClF4N4O2
    US9650358, Example 194
    —— (3-Ethoxy-6-methylpyridin-2-yl)-[2-[[5-(trifluoromethyl)pyridin-2-yl]oxymethyl]-7-azabicyclo[2.2.1]heptan-7-yl]methanone —— C22H24F3N3O3
    (3-Ethoxy-6-methylpyridin-2-yl)-[2-[[5-(trifluoromethyl)pyridin-2-yl]oxymethyl]-7-azabicyclo[2.2.1]heptan-7-yl]methanone
    —— 4-N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-1-N-[[(2S,3R)-2,5-dimethoxyoxolan-3-yl]methyl]cyclohexane-1,4-diamine —— C32H37ClFN5O3
    4-N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-1-N-[[(2S,3R)-2,5-dimethoxyoxolan-3-yl]methyl]cyclohexane-1,4-diamine
    —— (3R)-N-(5-chloro-4-{1-[2-(dimethylamino)-2-(3-fluorophenyl)ethyl]-1H-benzotriazol-6-yl}pyridin-2-yl)piperidine-3-carboxamide —— C27H29ClFN7O
    (3R)-N-(5-chloro-4-{1-[2-(dimethylamino)-2-(3-fluorophenyl)ethyl]-1H-benzotriazol-6-yl}pyridin-2-yl)piperidine-3-carboxamide
    —— 2-N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-2-N-ethyl-5,5-dioxo-5lambda6-thia-2-azaspiro[3.4]octane-2,8-dicarboxamide —— C29H28ClFN6O4S
    2-N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-2-N-ethyl-5,5-dioxo-5lambda6-thia-2-azaspiro[3.4]octane-2,8-dicarboxamide
    —— US9650358, Example 229 —— C29H28ClFN6S
    US9650358, Example 229
    —— 1-[2-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]pyrrolidin-1-yl]ethanone —— C20H20FN3O2
    1-[2-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]pyrrolidin-1-yl]ethanone
    —— (3R)-N-(5-chloro-4-{1-[3-(dimethylamino)propyl]-1H-benzimidazol-6-yl}pyridin-2-yl)piperidine-3-carboxamide —— C23H29ClN6O
    (3R)-N-(5-chloro-4-{1-[3-(dimethylamino)propyl]-1H-benzimidazol-6-yl}pyridin-2-yl)piperidine-3-carboxamide
    —— Tert-butyl 3-[[5-chloro-4-[1-(1,3-thiazol-4-ylmethyl)benzimidazol-5-yl]pyridin-2-yl]carbamoyl]piperidine-1-carboxylate —— C27H29ClN6O3S
    Tert-butyl 3-[[5-chloro-4-[1-(1,3-thiazol-4-ylmethyl)benzimidazol-5-yl]pyridin-2-yl]carbamoyl]piperidine-1-carboxylate
    —— Methyl 4-amino-3-chloro-6-(2,3-dihydro-1-benzofuran-6-yl)-5-fluoropyridine-2-carboxylate —— C15H12ClFN2O3
    Methyl 4-amino-3-chloro-6-(2,3-dihydro-1-benzofuran-6-yl)-5-fluoropyridine-2-carboxylate
    —— (1R,3S)-3-N-[5-chloro-4-[3-(oxan-4-ylmethyl)benzimidazol-5-yl]pyridin-2-yl]-1-N-(2-hydroxyethyl)-1-N-methylcyclohexane-1,3-dicarboxamide —— C29H36ClN5O4
    (1R,3S)-3-N-[5-chloro-4-[3-(oxan-4-ylmethyl)benzimidazol-5-yl]pyridin-2-yl]-1-N-(2-hydroxyethyl)-1-N-methylcyclohexane-1,3-dicarboxamide
    —— tert-butyl 4-(4-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)piperidine-1-carboxylate —— C24H29N3O3
    tert-butyl 4-(4-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)piperidine-1-carboxylate
    —— US9650358, Example 109 —— C26H25ClFN5
    US9650358, Example 109
    —— US9650358, Example 159 —— C26H25ClF3N5O
    US9650358, Example 159
    —— 4-[2-[3-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]pyrrolidin-1-yl]ethyl]morpholine —— C24H29FN4O2
    4-[2-[3-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]pyrrolidin-1-yl]ethyl]morpholine
    —— (3R)-N-(5-chloro-4-{1-[(1R)-1-(3-fluorophenyl)ethyl]-1H-benzimidazol-6-yl}pyridin-2-yl)piperidine-3-carboxamide —— C26H25ClFN5O
    (3R)-N-(5-chloro-4-{1-[(1R)-1-(3-fluorophenyl)ethyl]-1H-benzimidazol-6-yl}pyridin-2-yl)piperidine-3-carboxamide
    —— [(E)-1-pyridin-2-ylbut-1-en-2-yl]phosphane —— C9H12NP
    [(E)-1-pyridin-2-ylbut-1-en-2-yl]phosphane
    —— [2-[(5-Fluoropyridin-2-yl)oxymethyl]-7-azabicyclo[2.2.1]heptan-7-yl]-[6-methyl-3-(3-methyl-1,2-oxazol-5-yl)pyridin-2-yl]methanone —— C23H23FN4O3
    [2-[(5-Fluoropyridin-2-yl)oxymethyl]-7-azabicyclo[2.2.1]heptan-7-yl]-[6-methyl-3-(3-methyl-1,2-oxazol-5-yl)pyridin-2-yl]methanone
    —— US9650358, Example 234 —— C32H37ClFN5O3
    US9650358, Example 234
    —— 4-(5-fluoro-2-methoxyphenyl)-2-(1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile —— C21H19FN4O3S
    4-(5-fluoro-2-methoxyphenyl)-2-(1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile
    —— US9650358, Example 167 —— C28H27ClN6O
    US9650358, Example 167
    —— (3R)-N-(5-chloro-4-{1-[2-oxo-2-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-pyrrolo[3,2-b]pyridin-6-yl}pyridin-2-yl)piperidine-3-carboxamide —— C25H28ClN5O3
    (3R)-N-(5-chloro-4-{1-[2-oxo-2-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-pyrrolo[3,2-b]pyridin-6-yl}pyridin-2-yl)piperidine-3-carboxamide
    —— 6-bromo-5-chloro-N-(pyridin-4-ylmethyl)pyridin-2-amine —— C11H9BrClN3
    6-bromo-5-chloro-N-(pyridin-4-ylmethyl)pyridin-2-amine
    —— tert-butyl 3-(4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)azepane-1-carboxylate —— C25H30FN3O3
    tert-butyl 3-(4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)azepane-1-carboxylate
    —— 4-(5-chloro-2-methoxyphenyl)-2-piperidin-4-yl-1H-pyrrolo[2,3-b]pyridine —— C19H20ClN3O
    4-(5-chloro-2-methoxyphenyl)-2-piperidin-4-yl-1H-pyrrolo[2,3-b]pyridine
    —— (1S,5R)-6-[[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]carbamoyl]-3-azabicyclo[3.1.0]hexane-3-carboxylic acid —— C26H21ClFN5O3
    (1S,5R)-6-[[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]carbamoyl]-3-azabicyclo[3.1.0]hexane-3-carboxylic acid
    —— US9650358, Example 121 —— C26H25ClFN5
    US9650358, Example 121
    —— Tert-butyl 3-[[5-chloro-4-[3-(oxan-4-ylmethyl)benzimidazol-5-yl]pyridin-2-yl]carbamoyl]piperidine-1-carboxylate —— C29H36ClN5O4
    Tert-butyl 3-[[5-chloro-4-[3-(oxan-4-ylmethyl)benzimidazol-5-yl]pyridin-2-yl]carbamoyl]piperidine-1-carboxylate
    —— tert-butyl (1R,5S)-5-[2-fluoro-5-(5-fluoropyridin-3-yl)-4-(hydroxymethyl)phenyl]-5-(fluoromethyl)-3-[(2-methylpropan-2-yl)oxycarbonylimino]-2-oxa-4-azabicyclo[4.1.0]heptane-4-carboxylate —— C28H32F3N3O6
    tert-butyl (1R,5S)-5-[2-fluoro-5-(5-fluoropyridin-3-yl)-4-(hydroxymethyl)phenyl]-5-(fluoromethyl)-3-[(2-methylpropan-2-yl)oxycarbonylimino]-2-oxa-4-azabicyclo[4.1.0]heptane-4-carboxylate
    —— 3-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-5,5-dioxo-2-N-phenyl-5lambda6-thia-2-azaspiro[3.4]octane-2,8-dicarboxamide —— C33H28ClFN6O4S
    3-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-5,5-dioxo-2-N-phenyl-5lambda6-thia-2-azaspiro[3.4]octane-2,8-dicarboxamide
    —— [2-[(4,6-Dimethylpyrimidin-2-yl)oxymethyl]-7-azabicyclo[2.2.1]heptan-7-yl]-[6-methyl-2-(triazol-1-yl)pyridin-3-yl]methanone —— C22H25N7O2
    [2-[(4,6-Dimethylpyrimidin-2-yl)oxymethyl]-7-azabicyclo[2.2.1]heptan-7-yl]-[6-methyl-2-(triazol-1-yl)pyridin-3-yl]methanone
    —— [2-[(5-Methylpyridin-2-yl)oxymethyl]-7-azabicyclo[2.2.1]heptan-7-yl]-[6-methyl-2-(triazol-1-yl)pyridin-3-yl]methanone —— C22H24N6O2
    [2-[(5-Methylpyridin-2-yl)oxymethyl]-7-azabicyclo[2.2.1]heptan-7-yl]-[6-methyl-2-(triazol-1-yl)pyridin-3-yl]methanone
    —— tert-butyl 4-fluoro-3-(2-(1-methylpiperidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl)phenylcarbamate —— C24H29FN4O2
    tert-butyl 4-fluoro-3-(2-(1-methylpiperidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl)phenylcarbamate
    —— 2-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-2,2-dimethyl-3,6-dihydropyridin-1(2H)-yl}-N,N-dimethylacetamide —— C25H29FN4O2
    2-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-2,2-dimethyl-3,6-dihydropyridin-1(2H)-yl}-N,N-dimethylacetamide
    —— [3-[5-chloro-4-(6-fluoropyridin-2-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl]cyclohexyl]carbamic acid —— C19H18ClFN4O2
    [3-[5-chloro-4-(6-fluoropyridin-2-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl]cyclohexyl]carbamic acid
    —— 2-[4-(4-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]morpholine —— C18H18FN3O2
    2-[4-(4-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]morpholine
    —— 2-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}-1-(3-hydroxyazetidin-1-yl)ethanone —— C24H26F2N4O3
    2-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}-1-(3-hydroxyazetidin-1-yl)ethanone
    —— 5-chloro-6-[2-(1-methylpiperidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-N-(4H-1,2,4-triazol-3-ylmethyl)pyridin-2-amine —— C21H23ClN8
    5-chloro-6-[2-(1-methylpiperidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-N-(4H-1,2,4-triazol-3-ylmethyl)pyridin-2-amine
    —— 3-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]cyclohexan-1-amine —— C20H22FN3O
    3-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]cyclohexan-1-amine
    —— tert-butyl 4-[3-cyano-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylate —— C25H25FN4O3
    tert-butyl 4-[3-cyano-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylate
    —— 5-chloro-N-[(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)methyl]-6-[2-(1-methylpiperidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]pyridin-2-amine —— C24H30ClN5O2S
    5-chloro-N-[(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)methyl]-6-[2-(1-methylpiperidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]pyridin-2-amine
    —— tert-butyl 4-(4-(3-chloro-6-phenylpyridin-2-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl)piperidine-1-carboxylate —— C28H29ClN4O2
    tert-butyl 4-(4-(3-chloro-6-phenylpyridin-2-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl)piperidine-1-carboxylate
    —— 1-[4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl]-2-(2-hydroxyethylamino)ethanone —— C23H27FN4O3
    1-[4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl]-2-(2-hydroxyethylamino)ethanone
    —— 1,1-Dimethylethyl 4-[4-(6-amino-3-methoxy-2-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-1-piperidinecarboxylate —— C23H29N5O3
    1,1-Dimethylethyl 4-[4-(6-amino-3-methoxy-2-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-1-piperidinecarboxylate
    —— 4-(5-fluoro-2-methoxyphenyl)-2-(1-methylpyrrolidin-3-yl)-1H-pyrrolo[2,3-b]pyridine —— C19H20FN3O
    4-(5-fluoro-2-methoxyphenyl)-2-(1-methylpyrrolidin-3-yl)-1H-pyrrolo[2,3-b]pyridine
    —— 4-(4,5-difluoro-2-methoxyphenyl)-2-piperidin-3-yl-1H-pyrrolo[2,3-b]pyridine —— C19H19F2N3O
    4-(4,5-difluoro-2-methoxyphenyl)-2-piperidin-3-yl-1H-pyrrolo[2,3-b]pyridine
    —— US9650358, Example 188 —— C31H22ClFN6OS
    US9650358, Example 188
    —— tert-butyl 4-(4-(5-(tert-butoxycarbonylamino)-2-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)piperidine-1-carboxylate —— C28H35FN4O4
    tert-butyl 4-(4-(5-(tert-butoxycarbonylamino)-2-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)piperidine-1-carboxylate
    —— 4-(5-fluoro-2-methoxyphenyl)-2-[1-(oxan-3-ylmethyl)pyrrolidin-3-yl]-1H-pyrrolo[2,3-b]pyridine —— C24H28FN3O2
    4-(5-fluoro-2-methoxyphenyl)-2-[1-(oxan-3-ylmethyl)pyrrolidin-3-yl]-1H-pyrrolo[2,3-b]pyridine
    —— [4-Methyl-3-(triazol-2-yl)pyridin-2-yl]-[2-(pyridin-2-yloxymethyl)-7-azabicyclo[2.2.1]heptan-7-yl]methanone —— C21H22N6O2
    [4-Methyl-3-(triazol-2-yl)pyridin-2-yl]-[2-(pyridin-2-yloxymethyl)-7-azabicyclo[2.2.1]heptan-7-yl]methanone