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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡啶及其衍生物

    吡啶及其衍生物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 4-[3-cyano-5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide —— C22H19F2N5O2
    4-[3-cyano-5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide
    —— tert-butyl 4-(5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)-5,6-dihydropyridine-1(2H)-carboxylate —— C30H29F2N3O5S
    tert-butyl 4-(5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)-5,6-dihydropyridine-1(2H)-carboxylate
    —— 6-[2-(1-methylpiperidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-N-(2-phenylethyl)pyridin-2-amine —— C26H29N5
    6-[2-(1-methylpiperidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-N-(2-phenylethyl)pyridin-2-amine
    —— tert-butyl 4-(4-(6-((((2R,4R)-1-(tert-butoxycarbonyl)-4-fluoropyrrolidin-2-yl)methyl)amino)-3-chloropyridin-2-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl)piperidine-1-carboxylate —— C32H42ClFN6O4
    tert-butyl 4-(4-(6-((((2R,4R)-1-(tert-butoxycarbonyl)-4-fluoropyrrolidin-2-yl)methyl)amino)-3-chloropyridin-2-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl)piperidine-1-carboxylate
    —— 2-bromo-3-chloro-6-phenylpyridine —— C11H7BrClN
    2-bromo-3-chloro-6-phenylpyridine
    —— 1-[5-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,3a,6,6a-tetrahydro-1H-cyclopenta[c]pyrrol-2-yl]-2-hydroxyethanone —— C23H22FN3O3
    1-[5-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,3a,6,6a-tetrahydro-1H-cyclopenta[c]pyrrol-2-yl]-2-hydroxyethanone
    —— {4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}[(2R,4R)-4-hydroxypyrrolidin-2-yl]methanone —— C24H25FN4O3
    {4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}[(2R,4R)-4-hydroxypyrrolidin-2-yl]methanone
    —— [2-[(5-Fluoropyrimidin-2-yl)oxymethyl]-7-azabicyclo[2.2.1]heptan-7-yl]-[6-methyl-3-(1,3-oxazol-2-yl)pyridin-2-yl]methanone —— C21H20FN5O3
    [2-[(5-Fluoropyrimidin-2-yl)oxymethyl]-7-azabicyclo[2.2.1]heptan-7-yl]-[6-methyl-3-(1,3-oxazol-2-yl)pyridin-2-yl]methanone
    —— 5-chloro-N-[(1,1-dihydroxythian-4-yl)methyl]-6-[2-(1-methylpiperidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]pyridin-2-amine —— C24H32ClN5O2S
    5-chloro-N-[(1,1-dihydroxythian-4-yl)methyl]-6-[2-(1-methylpiperidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]pyridin-2-amine
    —— 5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile —— C21H23F2N3O2Si
    5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile
    —— 4-(5-fluoro-2-methoxyphenyl)-2-(pyrrolidin-3-yl)-1H-pyrrolo[2,3-b]pyridine —— C18H18FN3O
    4-(5-fluoro-2-methoxyphenyl)-2-(pyrrolidin-3-yl)-1H-pyrrolo[2,3-b]pyridine
    —— [3-(triazol-2-yl)pyridin-2-yl]-[(1S,2R,4R)-2-[[5-(trifluoromethyl)pyrazin-2-yl]amino]-7-azabicyclo[2.2.1]heptan-7-yl]methanone —— C19H17F3N8O
    [3-(triazol-2-yl)pyridin-2-yl]-[(1S,2R,4R)-2-[[5-(trifluoromethyl)pyrazin-2-yl]amino]-7-azabicyclo[2.2.1]heptan-7-yl]methanone
    —— 2-[(2R)-4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-2-(hydroxymethyl)-3,6-dihydro-2H-pyridin-1-yl]-N,N-dimethylacetamide —— C24H27FN4O3
    2-[(2R)-4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-2-(hydroxymethyl)-3,6-dihydro-2H-pyridin-1-yl]-N,N-dimethylacetamide
    —— N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-3-pyridin-3-yl-1,3-dihydropyrrolo[1,2-c][1,3]thiazole-7-carboxamide —— C31H22ClFN6OS
    N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-3-pyridin-3-yl-1,3-dihydropyrrolo[1,2-c][1,3]thiazole-7-carboxamide
    —— Tert-butyl 4-(6-fluoropyridin-2-yl)-2-[3-[(2-methylpropan-2-yl)oxycarbonylamino]cyclohexyl]pyrrolo[2,3-b]pyridine-1-carboxylate —— C28H35FN4O4
    Tert-butyl 4-(6-fluoropyridin-2-yl)-2-[3-[(2-methylpropan-2-yl)oxycarbonylamino]cyclohexyl]pyrrolo[2,3-b]pyridine-1-carboxylate
    —— 5-fluoro-4-(5-fluoro-2-methoxyphenyl)-2-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine —— C19H17F2N3O
    5-fluoro-4-(5-fluoro-2-methoxyphenyl)-2-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine
    —— (14R)-4,6,8-triamino-14-(2-chloro-6-fluorophenyl)-12-oxo-9-thia-3,11-diazatricyclo[8.4.0.02,7]tetradeca-1,3,5,7,10-pentaene-5-carbonitrile —— C18H12ClFN6OS
    (14R)-4,6,8-triamino-14-(2-chloro-6-fluorophenyl)-12-oxo-9-thia-3,11-diazatricyclo[8.4.0.02,7]tetradeca-1,3,5,7,10-pentaene-5-carbonitrile
    —— 2-[3-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]azetidin-1-yl]ethanamine —— C19H21FN4O
    2-[3-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]azetidin-1-yl]ethanamine
    —— 4-methyl-3-(2H-1,2,3-triazol-2-yl)picolinic acid —— C9H8N4O2
    4-methyl-3-(2H-1,2,3-triazol-2-yl)picolinic acid
    —— 6-bromo-5-chloro-N-((5-fluoropyridin-3-yl)methyl)pyridin-2-amine —— C11H8BrClFN3
    6-bromo-5-chloro-N-((5-fluoropyridin-3-yl)methyl)pyridin-2-amine
    —— [(1S,2R,4R)-2-[(5-fluoropyrimidin-2-yl)oxymethyl]-7-azabicyclo[2.2.1]heptan-7-yl]-[6-methyl-3-(4-methyl-1,3-oxazol-2-yl)pyridin-2-yl]methanone —— C22H22FN5O3
    [(1S,2R,4R)-2-[(5-fluoropyrimidin-2-yl)oxymethyl]-7-azabicyclo[2.2.1]heptan-7-yl]-[6-methyl-3-(4-methyl-1,3-oxazol-2-yl)pyridin-2-yl]methanone
    —— US9650358, Example 226 —— C31H30ClFN6
    US9650358, Example 226
    —— 4-N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-4-N-(pyridin-3-ylmethyl)cyclohexane-1,4-diamine —— C31H30ClFN6
    4-N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-4-N-(pyridin-3-ylmethyl)cyclohexane-1,4-diamine
    —— 4-(5-fluoro-2-methoxyphenyl)-3-methyl-2-piperidin-4-yl-1H-pyrrolo[2,3-b]pyridine —— C20H22FN3O
    4-(5-fluoro-2-methoxyphenyl)-3-methyl-2-piperidin-4-yl-1H-pyrrolo[2,3-b]pyridine
    —— (+/-)-(6-methyl-3-(2H-1,2,3-triazol-2-yl)pyridin-2-yl)(2-(((5-(trifluoromethyl)pyridin-2-yl)oxy)methyl)-7-azabicyclo[2.2.1]heptan-7-yl)methanone —— C22H21F3N6O2
    (+/-)-(6-methyl-3-(2H-1,2,3-triazol-2-yl)pyridin-2-yl)(2-(((5-(trifluoromethyl)pyridin-2-yl)oxy)methyl)-7-azabicyclo[2.2.1]heptan-7-yl)methanone
    —— 4-N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-4-N-[[3-(methoxymethyl)-1,2-dihydrotriazol-5-yl]methyl]cyclohexane-1,4-diamine —— C30H34ClFN8O
    4-N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-4-N-[[3-(methoxymethyl)-1,2-dihydrotriazol-5-yl]methyl]cyclohexane-1,4-diamine
    —— tert-butyl 4-(4-(5-chloro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)piperidine-1-carboxylate —— C24H28ClN3O3
    tert-butyl 4-(4-(5-chloro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)piperidine-1-carboxylate
    —— {(2S)-4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-1,2,3,6-tetrahydropyridin-2-yl}methanol —— C20H20FN3O2
    {(2S)-4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-1,2,3,6-tetrahydropyridin-2-yl}methanol
    —— 2-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}-N,N-dimethylacetamide —— C23H26F2N4O2
    2-{4-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}-N,N-dimethylacetamide
    —— tert-butyl 4-(4-(3-methoxypyridin-2-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl)piperidine-1-carboxylate —— C23H28N4O3
    tert-butyl 4-(4-(3-methoxypyridin-2-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl)piperidine-1-carboxylate
    —— 3-[4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydro-2H-pyridin-1-yl]-3-oxopropanenitrile —— C22H19FN4O2
    3-[4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydro-2H-pyridin-1-yl]-3-oxopropanenitrile
    —— 4-(5-fluoro-2-methoxyphenyl)-2-[1-(pyridin-4-ylmethyl)pyrrolidin-3-yl]-1H-pyrrolo[2,3-b]pyridine —— C24H23FN4O
    4-(5-fluoro-2-methoxyphenyl)-2-[1-(pyridin-4-ylmethyl)pyrrolidin-3-yl]-1H-pyrrolo[2,3-b]pyridine
    —— 5-fluoro-4-(5-fluoro-2-methoxyphenyl)-2-(1-{2-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl}-1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile —— C27H27F2N5O3
    5-fluoro-4-(5-fluoro-2-methoxyphenyl)-2-(1-{2-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl}-1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile
    —— 2-bromo-3-chloro-6-(pyridin-3-ylmethoxy)pyridine —— C11H8BrClN2O
    2-bromo-3-chloro-6-(pyridin-3-ylmethoxy)pyridine
    —— (S)-tert-butyl 4-(4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)-6-(((triisopropylsilyl)oxy)methyl)-5,6-dihydropyridine-1(2H)-carboxylate —— C34H48FN3O4Si
    (S)-tert-butyl 4-(4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)-6-(((triisopropylsilyl)oxy)methyl)-5,6-dihydropyridine-1(2H)-carboxylate
    —— 1-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}-2-(piperidin-1-yl)ethanone —— C26H31FN4O2
    1-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]piperidin-1-yl}-2-(piperidin-1-yl)ethanone
    —— 2-{3-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-8-azabicyclo[3.2.1]oct-2-en-8-yl}-N,N-dimethylacetamide —— C25H26F2N4O2
    2-{3-[5-fluoro-4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-8-azabicyclo[3.2.1]oct-2-en-8-yl}-N,N-dimethylacetamide
    —— [6-methyl-3-(triazol-2-yl)pyridin-2-yl]-[(1S,2R,4R)-2-[5-(trifluoromethyl)pyrimidin-2-yl]oxy-7-azabicyclo[2.2.1]heptan-7-yl]methanone —— C20H18F3N7O2
    [6-methyl-3-(triazol-2-yl)pyridin-2-yl]-[(1S,2R,4R)-2-[5-(trifluoromethyl)pyrimidin-2-yl]oxy-7-azabicyclo[2.2.1]heptan-7-yl]methanone
    —— [5-methyl-3-(triazol-2-yl)pyridin-2-yl]-[(1S,2R,4R)-2-[5-(trifluoromethyl)pyrimidin-2-yl]oxy-7-azabicyclo[2.2.1]heptan-7-yl]methanone —— C20H18F3N7O2
    [5-methyl-3-(triazol-2-yl)pyridin-2-yl]-[(1S,2R,4R)-2-[5-(trifluoromethyl)pyrimidin-2-yl]oxy-7-azabicyclo[2.2.1]heptan-7-yl]methanone
    —— N-[5-(trifluoromethyl)pyridin-2-yl]-7-azabicyclo[2.2.1]heptan-2-amine —— C12H14F3N3
    N-[5-(trifluoromethyl)pyridin-2-yl]-7-azabicyclo[2.2.1]heptan-2-amine
    —— (5-Bromo-2-ethoxypyridin-3-yl)-[2-(pyridin-2-yloxymethyl)-7-azabicyclo[2.2.1]heptan-7-yl]methanone —— C20H22BrN3O3
    (5-Bromo-2-ethoxypyridin-3-yl)-[2-(pyridin-2-yloxymethyl)-7-azabicyclo[2.2.1]heptan-7-yl]methanone
    —— 4-bromo-5-chloro-3-((1-(isopropylsulfonyl)piperidin-3-yl)ethynyl)pyridin-2-amine —— C15H19BrClN3O2S
    4-bromo-5-chloro-3-((1-(isopropylsulfonyl)piperidin-3-yl)ethynyl)pyridin-2-amine
    —— (5Z)-5-(aminomethylidene)-1,4-dimethyl-2,6-dioxopyridine-3-carbonitrile —— C9H9N3O2
    (5Z)-5-(aminomethylidene)-1,4-dimethyl-2,6-dioxopyridine-3-carbonitrile
    —— [6-methyl-3-(triazol-2-yl)pyridin-2-yl]-[(1S,2R,4R)-2-[5-(trifluoromethyl)pyrazin-2-yl]oxy-7-azabicyclo[2.2.1]heptan-7-yl]methanone —— C20H18F3N7O2
    [6-methyl-3-(triazol-2-yl)pyridin-2-yl]-[(1S,2R,4R)-2-[5-(trifluoromethyl)pyrazin-2-yl]oxy-7-azabicyclo[2.2.1]heptan-7-yl]methanone
    —— ethyl-[[4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydro-2H-pyridin-1-yl]sulfonyl]carbamic acid —— C22H23FN4O5S
    ethyl-[[4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydro-2H-pyridin-1-yl]sulfonyl]carbamic acid
    —— [6-Methyl-3-(triazol-2-yl)pyridin-2-yl]-[2-(pyrimidin-2-yloxymethyl)-7-azabicyclo[2.2.1]heptan-7-yl]methanone —— C20H21N7O2
    [6-Methyl-3-(triazol-2-yl)pyridin-2-yl]-[2-(pyrimidin-2-yloxymethyl)-7-azabicyclo[2.2.1]heptan-7-yl]methanone
    —— 1-(4-aminobutyl)pyridin-1-ium-3-carboxamide;N,N-diethylprop-2-enamide;1-(3-piperidin-1-ylpropyl)piperidine —— C30H55N6O2+
    1-(4-aminobutyl)pyridin-1-ium-3-carboxamide;N,N-diethylprop-2-enamide;1-(3-piperidin-1-ylpropyl)piperidine
    —— 4-fluoro-3-(2-(1-methylpiperidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-N-((tetrahydro-2H-pyran-4-yl)methyl)aniline —— C25H31FN4O
    4-fluoro-3-(2-(1-methylpiperidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-N-((tetrahydro-2H-pyran-4-yl)methyl)aniline
    —— 2-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-5,5-dimethylmorpholine —— C20H22FN3O2
    2-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-5,5-dimethylmorpholine
    —— 1-(1-aminobutyl)pyridin-1-ium-3-carboxamide;(E)-N-[(E)-pent-2-enoyl]pent-2-enamide;1-(3-piperidin-1-ylpropyl)piperidine —— C33H57N6O3+
    1-(1-aminobutyl)pyridin-1-ium-3-carboxamide;(E)-N-[(E)-pent-2-enoyl]pent-2-enamide;1-(3-piperidin-1-ylpropyl)piperidine