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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡啶及其衍生物

    吡啶及其衍生物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 1-[4-methoxy-5-[6-methyl-5-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxypyridin-2-yl]pyrimidin-2-yl]-N,N-dimethylpyrrolidin-3-amine —— C26H30N8O2
    1-[4-methoxy-5-[6-methyl-5-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxypyridin-2-yl]pyrimidin-2-yl]-N,N-dimethylpyrrolidin-3-amine
    —— 1-{[6-(difluoromethoxy)-5-(3-methoxyphenyl)pyridin-3-yl]methyl}-1H-1,2,4-triazol-3-amine —— C16H15F2N5O2
    1-{[6-(difluoromethoxy)-5-(3-methoxyphenyl)pyridin-3-yl]methyl}-1H-1,2,4-triazol-3-amine
    —— 3-[2-[[(1S)-1-[2,5-difluoro-4-(2-methylpyridin-4-yl)phenyl]ethyl]amino]-5-fluoropyrimidin-4-yl]-4-[(1S)-1-fluoroethyl]-1,3-oxazolidin-2-one —— C23H21F4N5O2
    3-[2-[[(1S)-1-[2,5-difluoro-4-(2-methylpyridin-4-yl)phenyl]ethyl]amino]-5-fluoropyrimidin-4-yl]-4-[(1S)-1-fluoroethyl]-1,3-oxazolidin-2-one
    —— (4R)-3-[2-[[(1S)-1-[2,5-difluoro-4-(2-methylpyridin-4-yl)phenyl]ethyl]amino]-5-fluoropyrimidin-4-yl]-4-[(1S)-1-fluoroethyl]-1,3-oxazolidin-2-one —— C23H21F4N5O2
    (4R)-3-[2-[[(1S)-1-[2,5-difluoro-4-(2-methylpyridin-4-yl)phenyl]ethyl]amino]-5-fluoropyrimidin-4-yl]-4-[(1S)-1-fluoroethyl]-1,3-oxazolidin-2-one
    —— (4R)-4-[(1S)-1-fluoroethyl]-3-[5-fluoro-2-[[(1S)-1-[5-[2-(trifluoromethyl)pyridin-4-yl]pyridin-2-yl]ethyl]amino]pyrimidin-4-yl]-1,3-oxazolidin-2-one —— C22H19F5N6O2
    (4R)-4-[(1S)-1-fluoroethyl]-3-[5-fluoro-2-[[(1S)-1-[5-[2-(trifluoromethyl)pyridin-4-yl]pyridin-2-yl]ethyl]amino]pyrimidin-4-yl]-1,3-oxazolidin-2-one
    —— 2-[4-[[5-(3-Chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl]methyl]phenyl]acetic acid —— C21H16ClF2NO3
    2-[4-[[5-(3-Chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl]methyl]phenyl]acetic acid
    —— 4-Methoxy-5-[6-methyl-5-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxypyridin-2-yl]-2-piperidin-1-ylpyrimidine —— C25H27N7O2
    4-Methoxy-5-[6-methyl-5-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxypyridin-2-yl]-2-piperidin-1-ylpyrimidine
    —— methyl 4-amino-3-chloro-6-(2,3,4-trichlorophenyl)picolinate —— C13H8Cl4N2O2
    methyl 4-amino-3-chloro-6-(2,3,4-trichlorophenyl)picolinate
    —— 2,5-Dioxo-1-(4-(pyridin-2-yldisulfanyl)butanoyloxy)pyrrolidine-3-sulfonic acid —— C13H14N2O7S3
    2,5-Dioxo-1-(4-(pyridin-2-yldisulfanyl)butanoyloxy)pyrrolidine-3-sulfonic acid
    —— 1-methyl-2H-pyridin-1-ium-1,5-disulfonate —— C6H8NO6S2-
    1-methyl-2H-pyridin-1-ium-1,5-disulfonate
    —— [1-({5-[2-(difluoromethoxy)pyridin-4-yl]-6-methoxypyridin-3-yl}methyl)-1H-1,2,4-triazol-3-yl]methanol —— C16H15F2N5O3
    [1-({5-[2-(difluoromethoxy)pyridin-4-yl]-6-methoxypyridin-3-yl}methyl)-1H-1,2,4-triazol-3-yl]methanol
    —— 1-(5-(hydroxymethyl)-4-phenyl-3,6-dihydropyridin-1(2H)-yl)ethan-1-one —— C14H17NO2
    1-(5-(hydroxymethyl)-4-phenyl-3,6-dihydropyridin-1(2H)-yl)ethan-1-one
    —— 4-amino-3-chloro-6-(4-chloro-3-fluoro-2-vinylphenyl)picolinic acid —— C14H9Cl2FN2O2
    4-amino-3-chloro-6-(4-chloro-3-fluoro-2-vinylphenyl)picolinic acid
    —— [5-(3-chlorophenyl)-6-methoxypyridin-3-yl](4-fluorophenyl)methanamine —— C19H16ClFN2O
    [5-(3-chlorophenyl)-6-methoxypyridin-3-yl](4-fluorophenyl)methanamine
    —— (1-{[5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl]methyl}-1H-imidazol-5-yl)methanol —— C17H14ClF2N3O2
    (1-{[5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl]methyl}-1H-imidazol-5-yl)methanol
    —— 4-methoxy-N-(1-methoxypropan-2-yl)-5-[6-methyl-5-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxypyridin-2-yl]pyrimidin-2-amine —— C24H27N7O3
    4-methoxy-N-(1-methoxypropan-2-yl)-5-[6-methyl-5-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxypyridin-2-yl]pyrimidin-2-amine
    —— 5-[[5-[2-(Difluoromethoxy)pyridin-4-yl]-6-ethoxypyridin-3-yl]methyl]pyrimidine-2-carboxamide —— C19H17F2N5O3
    5-[[5-[2-(Difluoromethoxy)pyridin-4-yl]-6-ethoxypyridin-3-yl]methyl]pyrimidine-2-carboxamide
    —— 6-(4-amino-5-chloro-6-(methoxycarbonyl)pyridin-2-yl)-3-chloro-2-fluorobenzoic acid —— C14H9Cl2FN2O4
    6-(4-amino-5-chloro-6-(methoxycarbonyl)pyridin-2-yl)-3-chloro-2-fluorobenzoic acid
    —— US9650358, Example 43 —— C26H22ClFN6
    US9650358, Example 43
    —— (4R)-4-[(1R)-1-[(2-methylpropan-2-yl)oxy]ethyl]-3-[2-[[(1S)-1-[6-[3-(trifluoromethyl)phenyl]pyridin-3-yl]ethyl]amino]pyrimidin-4-yl]-1,3-oxazolidin-2-one —— C27H30F3N5O3
    (4R)-4-[(1R)-1-[(2-methylpropan-2-yl)oxy]ethyl]-3-[2-[[(1S)-1-[6-[3-(trifluoromethyl)phenyl]pyridin-3-yl]ethyl]amino]pyrimidin-4-yl]-1,3-oxazolidin-2-one
    —— 4-Methoxy-2-[2-(methoxymethyl)pyrrolidin-1-yl]-5-[6-methyl-5-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxypyridin-2-yl]pyrimidine —— C26H29N7O3
    4-Methoxy-2-[2-(methoxymethyl)pyrrolidin-1-yl]-5-[6-methyl-5-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxypyridin-2-yl]pyrimidine
    —— 1-{[6-(difluoromethoxy)-5-[2-(difluoromethoxy)pyridin-4-yl]pyridin-3-yl]methyl}-1H-1,2,4-triazol-3-amine —— C15H12F4N6O2
    1-{[6-(difluoromethoxy)-5-[2-(difluoromethoxy)pyridin-4-yl]pyridin-3-yl]methyl}-1H-1,2,4-triazol-3-amine
    —— 1-[[1-[[4-[6-(Dimethylamino)pyridin-3-yl]phenyl]methyl]-5-(quinolin-2-ylmethoxy)benzimidazol-2-yl]methyl]cyclopentane-1-carboxylic acid —— C38H37N5O3
    1-[[1-[[4-[6-(Dimethylamino)pyridin-3-yl]phenyl]methyl]-5-(quinolin-2-ylmethoxy)benzimidazol-2-yl]methyl]cyclopentane-1-carboxylic acid
    —— (R)-3-(5-fluoro-2-(((S)-1-(4-methyl-2’-(trifluoromethyl)-[3,4’-bipyridin]-6-yl)ethyl)amino)pyrimidin-4-yl)-4-((S)-1-fluoroethyl)oxazolidin-2-one —— C23H21F5N6O2
    (R)-3-(5-fluoro-2-(((S)-1-(4-methyl-2’-(trifluoromethyl)-[3,4’-bipyridin]-6-yl)ethyl)amino)pyrimidin-4-yl)-4-((S)-1-fluoroethyl)oxazolidin-2-one
    —— 2-(1-{[5-(3-chlorophenyl)-6-methoxypyridin-3-yl]methyl}-1H-1,2,4-triazol-5-yl)propan-2-ol —— C18H19ClN4O2
    2-(1-{[5-(3-chlorophenyl)-6-methoxypyridin-3-yl]methyl}-1H-1,2,4-triazol-5-yl)propan-2-ol
    —— tert-butyl 5-(hydroxymethyl)-4-phenyl-3,6-dihydropyridine-1(2H)-carboxylate —— C17H23NO3
    tert-butyl 5-(hydroxymethyl)-4-phenyl-3,6-dihydropyridine-1(2H)-carboxylate
    —— 4-amino-5-chloro-3-methyl-6'-(trifluoromethyl)-[2,3'-bipyridine]-6-carboxylic acid —— C13H9ClF3N3O2
    4-amino-5-chloro-3-methyl-6'-(trifluoromethyl)-[2,3'-bipyridine]-6-carboxylic acid
    —— Tert-butyl 5-pyridin-2-yl-3,4,6,11-tetrazatricyclo[6.2.1.02,6]undeca-2,4-diene-11-carboxylate —— C17H21N5O2
    Tert-butyl 5-pyridin-2-yl-3,4,6,11-tetrazatricyclo[6.2.1.02,6]undeca-2,4-diene-11-carboxylate
    —— 3-(3-Chlorophenyl)-5-[(3-ethylpyrazol-1-yl)methyl]-2-methoxypyridine —— C18H18ClN3O
    3-(3-Chlorophenyl)-5-[(3-ethylpyrazol-1-yl)methyl]-2-methoxypyridine
    —— methyl 4-amino-3-chloro-6-(2,4-dichloro-3-fluorophenyl)-5-fluoropicolinate —— C13H7Cl3F2N2O2
    methyl 4-amino-3-chloro-6-(2,4-dichloro-3-fluorophenyl)-5-fluoropicolinate
    —— (3R)-N-(5-chloro-4-{1-[4-(methylsulfonyl)benzyl]-1H-benzotriazol-6-yl}pyridin-2-yl)piperidine-3-carboxamide —— C25H25ClN6O3S
    (3R)-N-(5-chloro-4-{1-[4-(methylsulfonyl)benzyl]-1H-benzotriazol-6-yl}pyridin-2-yl)piperidine-3-carboxamide
    —— 2,2-Dimethyl-3-[1-[(4-pyridin-3-ylphenyl)methyl]-5-(quinolin-2-ylmethoxy)benzimidazol-2-yl]propanoic acid —— C34H30N4O3
    2,2-Dimethyl-3-[1-[(4-pyridin-3-ylphenyl)methyl]-5-(quinolin-2-ylmethoxy)benzimidazol-2-yl]propanoic acid
    —— US9650358, Example 165 —— C27H27ClN4O3
    US9650358, Example 165
    —— 1-((5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl)methyl)-1H-1,2,4-triazole-3-carbaldehyde —— C16H11ClF2N4O2
    1-((5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl)methyl)-1H-1,2,4-triazole-3-carbaldehyde
    —— (S)-1-(6-(3-(trifluoromethyl)phenyl)pyridin-3-yl)ethanamine —— C14H13F3N2
    (S)-1-(6-(3-(trifluoromethyl)phenyl)pyridin-3-yl)ethanamine
    —— 1-(4-{[5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl]methyl}phenyl)cyclopropane-1-carboxamide —— C23H19ClF2N2O2
    1-(4-{[5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl]methyl}phenyl)cyclopropane-1-carboxamide
    —— 4-[[5-(3-Chlorophenyl)-6-methoxypyridin-3-yl]methyl]pyrazole-1-carboxylic acid —— C17H14ClN3O3
    4-[[5-(3-Chlorophenyl)-6-methoxypyridin-3-yl]methyl]pyrazole-1-carboxylic acid
    —— 2-Methoxy-3-(3-methoxyphenyl)-5-(1,2,4-triazol-1-ylmethyl)pyridine —— C16H16N4O2
    2-Methoxy-3-(3-methoxyphenyl)-5-(1,2,4-triazol-1-ylmethyl)pyridine
    —— 5-{[5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl]methyl}-N-methylpyridine-2-carboxamide —— C20H16ClF2N3O2
    5-{[5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl]methyl}-N-methylpyridine-2-carboxamide
    —— US9650358, Example 45 —— C27H23ClFN5
    US9650358, Example 45
    —— (6S,9R)-3-(pyridin-2-yl)-6,7,8,9-tetrahydro-5H-6,9-epimino[1,2,4]triazolo[4,3-a]azepine —— C12H13N5
    (6S,9R)-3-(pyridin-2-yl)-6,7,8,9-tetrahydro-5H-6,9-epimino[1,2,4]triazolo[4,3-a]azepine
    —— 3-(3-Chlorophenyl)-2-(difluoromethoxy)-5-(pyridin-3-ylmethyl)pyridine —— C18H13ClF2N2O
    3-(3-Chlorophenyl)-2-(difluoromethoxy)-5-(pyridin-3-ylmethyl)pyridine
    —— 4-N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-4-N-[(5,5-dimethyloxolan-2-yl)methyl]cyclohexane-1,4-diamine —— C32H37ClFN5O
    4-N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-4-N-[(5,5-dimethyloxolan-2-yl)methyl]cyclohexane-1,4-diamine
    —— (4R)-3-[2-[[(1S)-1-[2,5-difluoro-4-[2-(trifluoromethyl)pyridin-4-yl]phenyl]ethyl]amino]-5-fluoropyrimidin-4-yl]-4-[(1S)-1-fluoroethyl]-1,3-oxazolidin-2-one —— C23H18F7N5O2
    (4R)-3-[2-[[(1S)-1-[2,5-difluoro-4-[2-(trifluoromethyl)pyridin-4-yl]phenyl]ethyl]amino]-5-fluoropyrimidin-4-yl]-4-[(1S)-1-fluoroethyl]-1,3-oxazolidin-2-one
    —— 4-N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-4-N-(2-cyclohexyloxypropyl)cyclohexane-1,4-diamine —— C34H41ClFN5O
    4-N-[5-chloro-4-[3-[(3-fluorophenyl)methyl]benzimidazol-5-yl]pyridin-2-yl]-4-N-(2-cyclohexyloxypropyl)cyclohexane-1,4-diamine
    —— methyl 4-acetamido-3-chloro-6-(4-chloro-3-fluoro-2-(hydroxymethyl)phenyl)picolinate —— C16H13Cl2FN2O4
    methyl 4-acetamido-3-chloro-6-(4-chloro-3-fluoro-2-(hydroxymethyl)phenyl)picolinate
    —— (3R)-N-(5-chloro-4-{1-[2-(methylsulfonyl)ethyl]-1H-benzotriazol-6-yl}pyridin-2-yl)piperidine-3-carboxamide —— C20H23ClN6O3S
    (3R)-N-(5-chloro-4-{1-[2-(methylsulfonyl)ethyl]-1H-benzotriazol-6-yl}pyridin-2-yl)piperidine-3-carboxamide
    —— methyl 1-((5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl)methyl)-1H-imidazole-4-carboxylate —— C18H14ClF2N3O3
    methyl 1-((5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl)methyl)-1H-imidazole-4-carboxylate
    —— [(1S,8R)-5-(5-fluoropyridin-2-yl)-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]-[3-fluoro-2-(trifluoromethyl)pyridin-4-yl]methanone —— C19H13F5N6O2
    [(1S,8R)-5-(5-fluoropyridin-2-yl)-10-oxa-3,4,6,12-tetrazatricyclo[6.3.1.02,6]dodeca-2,4-dien-12-yl]-[3-fluoro-2-(trifluoromethyl)pyridin-4-yl]methanone
    —— (1-{[5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl]methyl}-1H-1,2,4-triazol-3-yl)methanamine —— C16H14ClF2N5O
    (1-{[5-(3-chlorophenyl)-6-(difluoromethoxy)pyridin-3-yl]methyl}-1H-1,2,4-triazol-3-yl)methanamine