N-((S)-1-(naphthalen-2-yl)allyloxy)-N-benzylacrylamide | 1004756-63-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N-((S)-1-(naphthalen-2-yl)allyloxy)-N-benzylacrylamide
• CAS: 1004756-63-1
• 化学式: C₂₃H₂₁NO₂
• 分子量: 343.425
• InChiKey: BZLMPGIVQURLNR-QFIPXVFZSA-N

反应信息

• 作为反应物：
  描述：

  N-((S)-1-(naphthalen-2-yl)allyloxy)-N-benzylacrylamide 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 作用下， 以 苯 为溶剂， 反应 10.0h， 生成 (S)-2-benzyl-6-(naphthalen-2-yl)-2H-1,2-oxazin-3(6H)-one 、 (R)-2-benzyl-6-(naphthalen-2-yl)-2H-1,2-oxazin-3(6H)-one
  参考文献：
  名称：

  Enantioselective synthesis of [1,2]-oxazinone scaffolds and [1,2]-oxazine core structures of FR900482

  摘要：

  Several chiral unsaturated [1,2]-oxazinone heterocycles have been synthesized by iridium-catalyzed allylic substitution and ring-closing metathesis (RCM) reaction in high yields with excellent enantiomeric excesses. In addition, the synthesis of [1,2]-oxazine core structures of FR900482 was achieved via iridiurn-catalyzed allylic substitution, followed by RCM and Heck reactions, respectively. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2007.07.071
• 作为产物：
  描述：

  、 丙烯酰氯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 生成 N-((S)-1-(naphthalen-2-yl)allyloxy)-N-benzylacrylamide
  参考文献：
  名称：

  Enantioselective synthesis of [1,2]-oxazinone scaffolds and [1,2]-oxazine core structures of FR900482

  摘要：

  Several chiral unsaturated [1,2]-oxazinone heterocycles have been synthesized by iridium-catalyzed allylic substitution and ring-closing metathesis (RCM) reaction in high yields with excellent enantiomeric excesses. In addition, the synthesis of [1,2]-oxazine core structures of FR900482 was achieved via iridiurn-catalyzed allylic substitution, followed by RCM and Heck reactions, respectively. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2007.07.071