7-(5-(benzothiazol-2-yl)thiophen-2-yl)-9,9-didecyl-N,N-diphenyl-9H-fluoren-2-amine | 1192875-30-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 7-(5-(benzothiazol-2-yl)thiophen-2-yl)-9,9-didecyl-N,N-diphenyl-9H-fluoren-2-amine
• 英文别名: 7-[5-(1,3-benzothiazol-2-yl)thiophen-2-yl]-9,9-didecyl-N,N-diphenylfluoren-2-amine
• CAS: 1192875-30-1
• 化学式: C₅₆H₆₄N₂S₂
• 分子量: 829.27
• InChiKey: JTEVJWVVLKPNJD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  20.9
• 重原子数：
  60
• 可旋转键数：
  23
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  72.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  碘苯 、 7-(5-(benzothiazol-2-yl)thiophen-2-yl)-9,9-didecyl-9H-fluoren-2-amine 在 18-冠醚-6 、 铜 、 potassium carbonate 作用下， 以 邻二氯苯 为溶剂， 反应 48.0h， 以94%的产率得到7-(5-(benzothiazol-2-yl)thiophen-2-yl)-9,9-didecyl-N,N-diphenyl-9H-fluoren-2-amine
  参考文献：
  名称：

  A Series of Fluorene-Based Two-Photon Absorbing Molecules: Synthesis, Linear and Nonlinear Characterization, and Bioimaging

  摘要：

  The synthesis, structural, and photophysical characterization of a series of new fluorescent donor acceptor and acceptor-acceptor molecules, based on the fluorenyl ring system, with two-photon absorbing properties is described. These new compounds exhibited large Stokes shifts, high fluorescence quantum yields, and significantly, high two-photon absorption cross sections, making them well suited for two-photon fluorescence microscopy imaging. Confocal and two-photon fluorescence microscopy imaging of COS-7 and HCT 116 cells incubated with probe I showed endosomal selectivity, demonstrating the potential of this class of fluorescent probes in multiphoton fluorescence microscopy.

  DOI：

  10.1021/jo1005075