dihydro-rhodamine 800 | 892121-50-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: dihydro-rhodamine 800
• 英文别名: 3-Oxa-9,23-diazaheptacyclo[17.7.1.15,9.02,17.04,15.023,27.013,28]octacosa-1(27),2(17),4(15),5(28),13,18-hexaene-16-carbonitrile
• CAS: 892121-50-5
• 化学式: C₂₆H₂₇N₃O
• 分子量: 397.52
• InChiKey: JSEXODXREFNDRS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  30
• 可旋转键数：
  0
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  39.5
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  rhodamine 800 在 sodium tetrahydroborate 作用下， 反应 2.0h， 生成 dihydro-rhodamine 800
  参考文献：
  名称：

  WO2006/65146

  摘要：

  公开号：

文献信息

• Fluorescent contrast agents
  申请人：GE HEALTHCARE AS

  公开号：EP2025349A2

  公开（公告）日：2009-02-18

  The invention relates to contrast agents for imaging of diseases associated with inflammations. More specifically the invention provides optical imaging contrast agents for imaging of activated leukocytes and methods for imaging of such. The contrast agent changes its fluorescent properties upon reaction with oxidants produced by the activated leukocytes.

  本发明涉及用于炎症相关疾病成像的造影剂。更具体地说，本发明提供了用于活化白细胞成像的光学成像造影剂及其成像方法。造影剂与活化白细胞产生的氧化剂反应后，其荧光特性会发生改变。
• Fluorescent Contrast Agent
  申请人：Tolleshaug Helge

  公开号：US20090238765A1

  公开（公告）日：2009-09-24

  The invention relates to contrast agents for imaging of diseases associated with inflammations. More specifically the invention provides optical imaging contrast agents for imaging of activated leukocytes and methods for imaging of such. The contrast agent changes its fluorescent properties upon reaction with oxidants produced by the activated leukocytes.
• FLUORESCENT CONTRAST AGENTS
  申请人：TOLLESHAUG HELGE

  公开号：US20110318273A1

  公开（公告）日：2011-12-29

  The invention relates to contrast agents for imaging of diseases associated with inflammations. More specifically the invention provides optical imaging contrast agents for imaging of activated leukocytes and methods for imaging of such. The contrast agent changes its fluorescent properties upon reaction with oxidants produced by the activated leukocytes.