2,5-Dibromfluorescein | 25709-88-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 2,5-Dibromfluorescein
• 英文别名: 2',5'-dibromo-3',6'-dihydroxy-spiro[phthalan-1,9'-xanthen]-3-one；2',5'-Dibrom-3',6'-dihydroxy-spiro[phthalan-1,9'-xanthen]-3-on；2',5'-dibromo-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
• CAS: 25709-88-0
• 化学式: C₂₀H₁₀Br₂O₅
• 分子量: 490.104
• InChiKey: UHEGRQRONCTEKB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  27
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 sodium hydroxide 、 溴 作用下， 生成 2,5-Dibromfluorescein
  参考文献：
  名称：

  Graichen; Molitor, Journal of the Association of Official Agricultural Chemists, 1959, vol. 42, p. 149,159

  摘要：

  DOI：

文献信息

• Leave-in color conditioner
  申请人：Pollack George

  公开号：US20050198746A1

  公开（公告）日：2005-09-15

  The invention is directed to novel hair dye compositions, novel leave-in conditioners, and novel leave-in conditioners with a hair coloring effect. Hair dye compositions, leave-in conditioners, and leave-in conditioners with hair coloring effect may include a styrene/vinylpyrrolidone copolymer emulsion.

  本发明涉及新型染发剂组合物、新型留香护发素以及具有染发效果的新型留香护发素。染发剂组合物、留香护发素和具有染发效果的留香护发素可能包括苯乙烯/吡咯烷酮共聚物乳液。
• Use of substituted quinone electron transfer agents in analytical determinations
  申请人：EASTMAN KODAK COMPANY (a New Jersey corporation)

  公开号：EP0190740A2

  公开（公告）日：1986-08-13

  Certain substituted benzo- and naphthoquinone electron transfer agents are useful in analytical compositions, elements and methods, e.g. for determinations of living cells. These electron transfer agents are capable of being reduced by an analyte, and the reduced electron transfer agent, in turn, reduces another compound providing a detectable species (e.g. a dye). The reduction potential (E1/2) of the electron transfer agents useful in this invention is in the range of from -320 to +400 mV as measured in an aqueous buffer solution at pH 7.

  某些取代的苯醌和萘醌电子转移剂可用于分析组合物、元素和方法中，例如用于测定活细胞。这些电子转移剂能够被分析物还原，被还原的电子转移剂反过来会还原另一种化合物，从而提供可检测的物质（如染料）。本发明中电子转移剂的还原电位（E1/2）在 pH 值为 7 的缓冲水溶液中的测量范围为 -320 至 +400 mV。
• Rapid differentiation of fungi from bacteria using polyene antibiotics
  申请人：EASTMAN KODAK COMPANY (a New Jersey corporation)

  公开号：EP0261931A2

  公开（公告）日：1988-03-30

  Rapid differentiation between viable fungi (for example, yeast) and viable bacteria is accomp­lished with certain polyene antibiotics which are used in combination with a compound which is normally reducible by both the fungi and the bacteria. The antibiotics selectively and substantially inhibit the reduction of the reducible compound by the fungi but do not affect the reducing capacity of the bacteria. The particular antibiotics useful are polyenes which selectively affect the function of the cytoplasmic membrane of fungi.

  某些多烯抗生素与真菌和细菌通常都能还原的化合物结合使用，可以快速区分有生命力的真菌（例如酵母）和有生命力的细菌。抗生素选择性地、实质性地抑制真菌还原可还原化合物，但不影响细菌的还原能力。特别有用的抗生素是选择性影响真菌细胞质膜功能的多烯类抗生素。
• Water-compatible reducible compounds and their use in analytical compositions and methods
  申请人：EASTMAN KODAK COMPANY (a New Jersey corporation)

  公开号：EP0247848A2

  公开（公告）日：1987-12-02

  Certain water-compatible reducible compounds are useful in analytical compositions and elements for assay of various analytes, for example, microorganisms. These compounds comprise a moiety which provides a detectable species (for example, a dye) when released from the compound at physiological pH. Further, these compounds are aromatic derivatives or quinones having water-compatibilizing substituents which allow them to be used in compositions without the use of surfactants.

  某些与水相容的还原性化合物可用于分析组合物和元素中，以检测各种分析物，例如微生物。 这些化合物包含一个分子，当在生理 pH 值下从化合物中释放出来时，该分子可提供一种可检测的物质（例如染料）。 此外，这些化合物是芳香族衍生物或醌类化合物，具有与水相容的取代基，使其无需使用表面活性剂即可用于组合物中。
• Use of organic buffers to reduce dehydroascorbic acid interference in analytical methods
  申请人：EASTMAN KODAK COMPANY (a New Jersey corporation)

  公开号：EP0259133A2

  公开（公告）日：1988-03-09

  The interference of dehydroascorbic acid, an oxidation product of ascorbic acid, in analytical methods is reduced with the use of certain nitrogen-containing organic buffers. Dehydroascorbic acid tends to cause premature reduction of reducible compounds which are used to provide detectable species in the presence of an analyte. These organic buffers, as opposed to inorganic buffers, prevent premature reduction of the reducible compounds. An analytical method can be carried out in solution or in a dry analytical element.

  使用某些含氮有机缓冲剂可减少抗坏血酸的氧化产物脱氢抗坏血酸对分析方法的干扰。 脱氢抗坏血酸往往会导致还原性化合物过早还原，而还原性化合物用于在分析物存在时提供可检测物种。 与无机缓冲剂相比，这些有机缓冲剂可防止还原性化合物过早还原。 分析方法可在溶液或干燥的分析元件中进行。