2-((Z)-2-Fluoro-3-methyl-4-trityloxy-but-2-enyl)-isoindole-1,3-dione | 205035-68-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: 2-((Z)-2-Fluoro-3-methyl-4-trityloxy-but-2-enyl)-isoindole-1,3-dione
• 英文别名: 2-[(Z)-2-fluoro-3-methyl-4-trityloxybut-2-enyl]isoindole-1,3-dione
• CAS: 205035-68-3
• 化学式: C₃₂H₂₆FNO₃
• 分子量: 491.562
• InChiKey: PBODETWRTXSPBX-FAJYDZGRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  37
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  46.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-((Z)-2-Fluoro-3-methyl-4-trityloxy-but-2-enyl)-isoindole-1,3-dione 在 对甲苯磺酸 作用下， 以 甲醇 为溶剂， 反应 48.0h， 以66%的产率得到2-((Z)-2-Fluoro-4-hydroxy-3-methyl-but-2-enyl)-isoindole-1,3-dione
  参考文献：
  名称：

  Synthesis and Cytokinin Activity of New Zeatin Derivatives

  摘要：

  The analogue of zeatin bearing a vinylic fluorine atom and its geometrical isomer were synthesized. The fluorine atom exerts a favorable influence on cytokinin activity in the fluoro analogue of cis-zeatin, but not in the fluoro analogue of zeatin itself. Another series of zeatin derivatives in which the methyl group was replaced by alkyl (ethyl, propyl, and isopropyl), phenyl, and benzyl groups were also obtained. The ethyl analogue was found to be more active than zeatin, while the others were inactive or slightly active.

  DOI：

  10.1021/jf970752l
• 作为产物：
  描述：

  (((2-methylallyl)oxy)methanetriyl)tribenzene 在 sodium hydroxide 、 苄基三乙基氯化铵 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 108.0h， 生成 2-((Z)-2-Fluoro-3-methyl-4-trityloxy-but-2-enyl)-isoindole-1,3-dione
  参考文献：
  名称：

  Synthesis and Cytokinin Activity of New Zeatin Derivatives

  摘要：

  The analogue of zeatin bearing a vinylic fluorine atom and its geometrical isomer were synthesized. The fluorine atom exerts a favorable influence on cytokinin activity in the fluoro analogue of cis-zeatin, but not in the fluoro analogue of zeatin itself. Another series of zeatin derivatives in which the methyl group was replaced by alkyl (ethyl, propyl, and isopropyl), phenyl, and benzyl groups were also obtained. The ethyl analogue was found to be more active than zeatin, while the others were inactive or slightly active.

  DOI：

  10.1021/jf970752l

文献信息

• Synthesis and Cytokinin Activity of New Zeatin Derivatives
  作者：M'Barek Haidoune、Isabelle Raynaud、Norval O'Connor、Pascal Richomme、René Mornet、Michel Laloue

  DOI：10.1021/jf970752l

  日期：1998.4.1

  The analogue of zeatin bearing a vinylic fluorine atom and its geometrical isomer were synthesized. The fluorine atom exerts a favorable influence on cytokinin activity in the fluoro analogue of cis-zeatin, but not in the fluoro analogue of zeatin itself. Another series of zeatin derivatives in which the methyl group was replaced by alkyl (ethyl, propyl, and isopropyl), phenyl, and benzyl groups were also obtained. The ethyl analogue was found to be more active than zeatin, while the others were inactive or slightly active.