[1,2']Binaphthalenyl-1'-carboxylic acid diisopropylamide | 132464-45-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: [1,2']Binaphthalenyl-1'-carboxylic acid diisopropylamide
• 英文别名: 2-naphthalen-1-yl-N,N-di(propan-2-yl)naphthalene-1-carboxamide
• CAS: 132464-45-0
• 化学式: C₂₇H₂₇NO
• 分子量: 381.517
• InChiKey: JKVMJNKMJCQPKY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  29
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  [1,2']Binaphthalenyl-1'-carboxylic acid diisopropylamide 在 铬酸 、 lithium diisopropyl amide 作用下， 生成 13H-二苯并[a,g]芴-13-酮
  参考文献：
  名称：

  Remote aromatic metalation. An anionic Friedel-Crafts equivalent for the regioselective synthesis of condensed fluorenones from biaryl and m-teraryl 2-amides

  摘要：

  Remote metalation (t-BuLi, LDA) of m-teraryl and biaryl amides (Scheme I) constitutes a short and convenient route to a variety of substituted and condensed fluorenones, including aza analogues (Table I) and the natural product, dengibsinin (6a, Scheme II).

  DOI：

  10.1021/jo00005a004

文献信息

• FU, JIAN-MIN;ZHAO, BAO-PING;SHARP, M. J.;SNIECKUS, V., J. ORG. CHEM., 56,(1991) N, C. 1683-1685
  作者：FU, JIAN-MIN、ZHAO, BAO-PING、SHARP, M. J.、SNIECKUS, V.

  DOI：——

  日期：——
• Remote aromatic metalation. An anionic Friedel-Crafts equivalent for the regioselective synthesis of condensed fluorenones from biaryl and m-teraryl 2-amides
  作者：Jian Min Fu、Bao Ping Zhao、M. J. Sharp、V. Snieckus

  DOI：10.1021/jo00005a004

  日期：1991.3

  Remote metalation (t-BuLi, LDA) of m-teraryl and biaryl amides (Scheme I) constitutes a short and convenient route to a variety of substituted and condensed fluorenones, including aza analogues (Table I) and the natural product, dengibsinin (6a, Scheme II).