2-[(E)-2-naphthalen-1-ylethenyl]-5-nitroaniline | 1414870-13-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 2-[(E)-2-naphthalen-1-ylethenyl]-5-nitroaniline
• CAS: 1414870-13-5
• 化学式: C₁₈H₁₄N₂O₂
• 分子量: 290.321
• InChiKey: CAKMKBGZQVEUDN-CMDGGOBGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  71.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  trans-1-(2.4-dinitro-phenyl)-2-(naphthyl-(1))-ethylene 在 sodium azide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 20.0h， 以75%的产率得到2-[(E)-2-naphthalen-1-ylethenyl]-5-nitroaniline
  参考文献：
  名称：

  A novel regioselective method for aminostilbene preparation—the role of sodium azide

  摘要：

  The reaction between a derivative of 2,4-dinitrostilbene and sodium azide gave consistently 2-amino-4-nitrostilbenes as the sole products instead of the expected azidonitrostilbene. Based on this finding, we present a one-step preparative method for selective transformation of the ortho-NO2 group in (E)-2,4-dinitrostilbenes into an ortho-NH2 group to give (E)-2-amino-4-nitrostilbenes. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.09.066

文献信息

• A novel regioselective method for aminostilbene preparation—the role of sodium azide
  作者：Katarzyna Janowska、Rafał Matczak、Jacek Zakrzewski、Hanna Krawczyk

  DOI：10.1016/j.tetlet.2012.09.066

  日期：2012.11

  The reaction between a derivative of 2,4-dinitrostilbene and sodium azide gave consistently 2-amino-4-nitrostilbenes as the sole products instead of the expected azidonitrostilbene. Based on this finding, we present a one-step preparative method for selective transformation of the ortho-NO2 group in (E)-2,4-dinitrostilbenes into an ortho-NH2 group to give (E)-2-amino-4-nitrostilbenes. (C) 2012 Elsevier Ltd. All rights reserved.