S-(4-trimethoxysilyl)benzyl S'-propyltrithiocarbonate | 1355342-80-1

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: S-(4-trimethoxysilyl)benzyl S'-propyltrithiocarbonate
• CAS: 1355342-80-1
• 化学式: C₁₄H₂₂O₃S₃Si
• 分子量: 362.61
• InChiKey: NCGVALHUCKHAPA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.43
• 重原子数：
  21.0
• 可旋转键数：
  8.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  27.69
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为产物：
  描述：

  二硫化碳 、 丙烷-1-硫醇 、 4-(氯甲基)苯基三甲氧基硅烷 在 potassium phosphate 作用下， 以 丙酮 为溶剂， 反应 13.67h， 生成 S-(4-trimethoxysilyl)benzyl S'-propyltrithiocarbonate
  参考文献：
  名称：

  Gold/quantum dot nanoprobe for detecting active ricin in complex matrix and application thereof

  摘要：

  本公开涉及一种用于检测复杂基质中活性蓖麻毒蛋白的金/量子点纳米探针及其应用。所述金/量子点纳米探针是一种纳米探针，其通过利用经单链寡脱氧核苷酸（ssODN）修饰的金纳米粒子和量子点在碱基配对杂交模式下形成双链寡脱氧核苷酸，并将金纳米粒子和量子点组装成核-卫星结构。根据本公开，所述金/量子点纳米探针用于检测活性蓖麻毒蛋白，其检测限为7.46 ng/mL，具有高准确性和良好的可靠性，且无需大型设备和复杂操作。为了进一步消除假阳性结果，本公开还提供了一种利用磁珠在复杂样本中富集蓖麻毒蛋白的方法。在无需确切活性蓖麻毒蛋白浓度的情况下，本公开提供的金/量子点纳米探针可通过荧光的淬灭及开启作用实现裸眼可视化检测。

  公开号：

  US11391711B2

文献信息

• One-Pot Controlled Synthesis of Homopolymers and Diblock Copolymers Grafted Graphene Oxide Using Couplable RAFT Agents
  作者：Kun Jiang、Chunnuan Ye、Peipei Zhang、Xiaosong Wang、Youliang Zhao

  DOI：10.1021/ma2024655

  日期：2012.2.14

  An original strategy is presented to synthesize homopolymers and diblock copolymers grafted graphene oxide by simultaneous coupling reaction and RAFT process. Z-functionalized S-methoxycarbonylphenylmethyl S'-3-(trimethoxysilyl)propyltrithiocarbonate (MPTT) and R-functionalized S-4-(trimethoxysilyl)benzyl S'-propyltrithiocarbonate (TBPT) were used as couplable RAFT agents to prepare the target nanocomposites. Under similar conditions, MPTT-mediated grafting reaction was liable to afford grafted chains with shorter chain length, narrower molecular weight distribution and lower grafting density than TBPT-based reaction owing to increased shielding effect and different grafting process. The grafted polymers had nearly controlled molecular weight and polydispersity ranging between 1.11 and 1.38, and the apparent molar grafting ratio was estimated to be 73.6-220 mu mol/g as the molecular weights of grafted polymers were in the range of 3980-12500 g/mol. The improved solubility and dispersibility of GO-polymer composites in various solvents comprising hexane and water confirmed their amphiphilicity. The grafting process offers an opportunity to alter GO morphologies, and surface morphologies involving nanosheets, nanoparticles, and nanorods were observed as the composites were dispersed in different solvents with the aid of sonication treatment. This tandem approach is promising for surface modification of solid substrates with hydroxyl surface due to its mild conditions, straightforward synthesis and good controllability.