4-Mercapto-[1]naphthol | 45993-54-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4-Mercapto-[1]naphthol
• 英文别名: 4-Hydroxy-naphthalinthiol-(1)；4-Hydroxy-1-mercapto-naphthalin；4-Hydroxy-naphthyl-(1)-mercaptan；Monothio-α-naphthohydrochinon；1-Thio-4-hydroxy-naphthalene；4-Sulfanylnaphthalen-1-ol
• CAS: 45993-54-2
• 化学式: C₁₀H₈OS
• mdl: MFCD19301479
• 分子量: 176.239
• InChiKey: KYDWNVBQXHQXPT-UHFFFAOYSA-N

物化性质

• 熔点：
  114 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
• 沸点：
  370.9±25.0 °C(Predicted)
• 密度：
  1.309±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  21.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-Mercapto-[1]naphthol 在 乙醇 、 双氧水 作用下， 生成 二(4-羟基-1-萘基)二硫醚
  参考文献：
  名称：

  Kaufmann; Liepe, Berichte der Deutschen Pharmazeutischen Gesellschaft, vol. 33, p. 148

  摘要：

  DOI：
• 作为产物：
  描述：

  4-thiocyanatonaphthalen-1-ol 在 盐酸 、 锌 作用下， 生成 4-Mercapto-[1]naphthol
  参考文献：
  名称：

  Kaufmann; Liepe, Berichte der Deutschen Pharmazeutischen Gesellschaft, vol. 33, p. 148

  摘要：

  DOI：

文献信息

• Process for production of vinyl chloride polymer
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP0172427A2

  公开（公告）日：1986-02-26

  This process is a process for production of a vinyl chloride polymer by suspension polymerization or emulsion polymerization of vinyl chloride monomer or a mixture of vinyl chloride monomer with a vinyl monomer copolymerizable with said vinyl chloride monomer in an aqueous medium, characterized in that the polymerization is carried out in a polymerizer, the inner wall surface and portions of the auxiliary equipment thereof which may come into contact with the monomer during polymerization being previously coated with a scaling preventive comprising at least one selected from dyes, pigments and aromatic or heterocyclic compounds having at least 5 conjugated π bonds, while controlling the chloride ion concentration in the reaction mixture to not higher than 100 ppm. According to said process, scaling onto the inner wall surface of a polymerizer, etc. during polymerization can be prevented effectively and surely.

  该工艺是通过氯乙烯单体或氯乙烯单体与可与所述氯乙烯单体共聚的乙烯基单体混合物在水介质中进行悬浮聚合或乳液聚合来生产氯乙烯聚合物的工艺，其特征在于聚合是在聚合器中进行的、内壁表面及其辅助设备中可能在聚合过程中与单体接触的部分事先涂上一层防垢剂，该防垢剂至少包括一种选自染料、颜料和至少有 5 个共轭 π 键的芳香族或杂环化合物的防垢剂，同时控制反应混合物中的氯离子浓度不高于 100 ppm。根据上述工艺，可有效、可靠地防止聚合过程中聚合器等内壁表面结垢。
• Effects of oxygen–sulfur substitution on glycosaminoglycan-priming naphthoxylosides
  作者：Mårten Jacobsson、Katrin Mani、Ulf Ellervik

  DOI：10.1016/j.bmc.2007.05.008

  日期：2007.8

  Three series of sulfur-containing analogs to the selectively antiproliferative 2-(6-hydroxynaphthyl) beta-D-xylopyranoside were synthesized and their biological properties investigated. A short, general route to hydroxynaphthyl disulfides from dihydroxy-naphthalenes was developed to utilize the disulfide bond as a sulfur-selective protecting group to enable the orthogonal protection of hydroxyls and thiols. The results indicate that hydrophobic, uncharged oxygen-sulfur substituted naphthoxylosides are taken up by calls and initiate priming of GAG chains to a greater extent compared to the oxygen analogs. No correlation between priming ability and antiproliferative activity was observed. (c) 2007 Elsevier Ltd. All rights reserved.
• Zincke; Ruppersberg, Chemische Berichte, 1915, vol. 48, p. 123
  作者：Zincke、Ruppersberg

  DOI：——

  日期：——
• US2004728
  申请人：——

  公开号：——

  公开（公告）日：——
• GB383284
  申请人：——

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