1-<(2-Naphthylamino)methyl>-2-naphthol | 6642-10-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-<(2-Naphthylamino)methyl>-2-naphthol
• 英文别名: 1-[2]Naphthylaminomethyl-[2]naphthol；1-[(Naphthalen-2-ylamino)methyl]naphthalen-2-ol
• CAS: 6642-10-0
• 化学式: C₂₁H₁₇NO
• 分子量: 299.372
• InChiKey: FDLFDSDZJXCTHE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  32.3
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-<(2-Naphthylamino)methyl>-2-naphthol 在 吡啶 、 盐酸羟胺 作用下， 以 甲苯 为溶剂， 反应 2.0h， 生成 二苯并(A,J)丫啶
  参考文献：
  名称：

  杂环螺环己二烯酮，第 1 部分

  摘要：

  描述为亚甲胺 3 的化合物被认为是杂环螺环己二烯酮 9，催化加氢，与文献相反，不会产生甲胺衍生物 4，而是产生螺酮 10 和非对映异构体螺环醇 11a / 11b 的混合物。研究了 9 对质子酸和羰基试剂的反应性。

  DOI：

  10.1002/ardp.19923251009
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 乙酸乙酯 、 铂 作用下， 生成 1-<(2-Naphthylamino)methyl>-2-naphthol
  参考文献：
  名称：

  Efficacy Beliefs, Background Variables, and Differentiated Instruction of Israeli Prospective Teachers

  摘要：

  in this study, the authors examined efficacy beliefs and choices of differentiated instructional strategies needed for effective teaching in inclusive classrooms. Participants included 191 Israeli prospective teachers. They responded to a modified form of the Teacher Efficacy Scale (Gibson & Dembo, 1984) and a 59-item instructional strategies scale. Findings revealed that the Personal Teaching Efficacy factor (PTE) was related to choices of instruction, but the Teaching Efficacy factor (TE) was not. Prospective teachers focusing on junior high education obtained the highest PTE scores compared with those focusing on early childhood and elementary education, and participants focusing on early childhood education obtained the highest TE scores. Participants expressed intent to make adaptations directed toward all students and less willingness to use differentiated instruction.

  DOI：

  10.1080/00220670209598791

文献信息

• Reaction of 2-Naphthol with Formaldehyde and 2-Naphthylamine. Isolation of 1-(2-Naphthylaminomethyl)-2-naphthol
  作者：W. J. Burke、Leo G. Adams、K. Chadwick Murdock、Sven H. Ruetman

  DOI：10.1021/ja01626a051

  日期：1955.11
• Efficacy Beliefs, Background Variables, and Differentiated Instruction of Israeli Prospective Teachers
  作者：Cheruta Wertheim、Yona Leyser

  DOI：10.1080/00220670209598791

  日期：2002.9

  in this study, the authors examined efficacy beliefs and choices of differentiated instructional strategies needed for effective teaching in inclusive classrooms. Participants included 191 Israeli prospective teachers. They responded to a modified form of the Teacher Efficacy Scale (Gibson & Dembo, 1984) and a 59-item instructional strategies scale. Findings revealed that the Personal Teaching Efficacy factor (PTE) was related to choices of instruction, but the Teaching Efficacy factor (TE) was not. Prospective teachers focusing on junior high education obtained the highest PTE scores compared with those focusing on early childhood and elementary education, and participants focusing on early childhood education obtained the highest TE scores. Participants expressed intent to make adaptations directed toward all students and less willingness to use differentiated instruction.
• Heterocyclische Spirocyclohexadienone, 1. Mitteilung
  作者：Hans Möhrle、Dieter Schake、Karin Bluhme-Hensen

  DOI：10.1002/ardp.19923251009

  日期：——

  Die als Methylenamin 3 beschriebene Verbindung wird als heterocyclisches Spirocyclohexadienon 9 erkannt, wobei die katalytische Hydrierung entgegen den Literaturangaben nicht zum Methylaminderivat 4, sondern zum Spiroketon 10 und einem Gemisch diastereomerer, spirocyclischer Alkohole 11a/11b führt. Die Reaktivität von 9 gegenüber Protonensäuren und Carbonylreagentien wird untersucht.

  描述为亚甲胺 3 的化合物被认为是杂环螺环己二烯酮 9，催化加氢，与文献相反，不会产生甲胺衍生物 4，而是产生螺酮 10 和非对映异构体螺环醇 11a / 11b 的混合物。研究了 9 对质子酸和羰基试剂的反应性。