2-(3-iodoprop-2-ynyloxy)naphthalene | 22176-95-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-(3-iodoprop-2-ynyloxy)naphthalene
• 英文别名: 2-[(3-Iodoprop-2-yn-1-yl)oxy]naphthalene；2-(3-iodoprop-2-ynoxy)naphthalene
• CAS: 22176-95-0
• 化学式: C₁₃H₉IO
• 分子量: 308.118
• InChiKey: SOWWTRBWGREZOF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-(2-炔丙基氧代)萘 在 叔丁基过氧化氢 、 potassium iodide 作用下， 以 甲醇 、 水 为溶剂， 反应 6.0h， 以62%的产率得到2-(3-iodoprop-2-ynyloxy)naphthalene
  参考文献：
  名称：

  Mild and efficient oxy-iodination of alkynes and phenols with potassium iodide and tert-butyl hydroperoxide

  摘要：

  An efficient synthesis of 1-iodoalkynes and iodophenols was easily achieved by employing simple KI and TBHP. The reaction does not involve the use of a metal and base combination. A variety of substituted alkynes and phenols were prepared with good to excellent yield. (c) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.02.074

文献信息

• Mild and efficient oxy-iodination of alkynes and phenols with potassium iodide and tert-butyl hydroperoxide
  作者：K. Rajender Reddy、M. Venkateshwar、C. Uma Maheswari、P. Santhosh Kumar

  DOI：10.1016/j.tetlet.2010.02.074

  日期：2010.4

  An efficient synthesis of 1-iodoalkynes and iodophenols was easily achieved by employing simple KI and TBHP. The reaction does not involve the use of a metal and base combination. A variety of substituted alkynes and phenols were prepared with good to excellent yield. (c) 2010 Elsevier Ltd. All rights reserved.