3,4-dihydro-3-phenyl-H-2-benzopyran-1-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 3,4-dihydro-3-phenyl-H-2-benzopyran-1-ol
• 英文别名: 3-Phenylisochroman-1-ol；3-phenyl-3,4-dihydro-1H-isochromen-1-ol
• 化学式: C₁₅H₁₄O₂
• 分子量: 226.275
• InChiKey: YHVDJDASXIMISF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-phenylisochroman 在 二甲基二环氧乙烷 作用下， 以 丙酮 为溶剂， 反应 6.0h， 以61%的产率得到3,4-dihydro-3-phenyl-H-2-benzopyran-1-ol
  参考文献：
  名称：

  Oxidation of 3-arylisochromans by dimethyldioxirane. An easy route to substituted 3-arylisocoumarins

  摘要：

  The selective oxidation of the two different benzylethereal position of 3-arylisochromans by dimethyldioxirane as a function of different substituents on the aromatic rings was studied. The easy oxidation of these compounds was exploited for a new easy access to substituted 3-arylisocoumarins. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(99)00917-5

文献信息

• Oxidation of 3-arylisochromans by dimethyldioxirane. An easy route to substituted 3-arylisocoumarins
  作者：Paolo Bovicelli、Paolo Lupattelli、Benedetta Crescenzi、Anna Sanetti、Roberta Bernini

  DOI：10.1016/s0040-4020(99)00917-5

  日期：1999.12

  The selective oxidation of the two different benzylethereal position of 3-arylisochromans by dimethyldioxirane as a function of different substituents on the aromatic rings was studied. The easy oxidation of these compounds was exploited for a new easy access to substituted 3-arylisocoumarins. (C) 1999 Elsevier Science Ltd. All rights reserved.