bis(4-bis(4-fluorophenyl)methylphenyl)methyl-trimethylsilane | 1048954-71-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: bis(4-bis(4-fluorophenyl)methylphenyl)methyl-trimethylsilane
• 英文别名: Bis[4-[bis(4-fluorophenyl)methyl]phenyl]methyl-trimethylsilane；bis[4-[bis(4-fluorophenyl)methyl]phenyl]methyl-trimethylsilane
• CAS: 1048954-71-7
• 化学式: C₄₂H₃₆F₄Si
• 分子量: 644.827
• InChiKey: PKNXBMKHHUZZOJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.61
• 重原子数：
  47
• 可旋转键数：
  9
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  bis(4-bis(4-fluorophenyl)methylphenyl)methyl-trimethylsilane 在 三氟甲磺酸 、 tetrabutylammonium tetrafluoroborate 、 三乙基硅烷 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 1.17h， 以50%的产率得到1-[Bis(4-fluorophenyl)methyl]-4-[[4-[bis(4-fluorophenyl)methyl]phenyl]methyl]benzene
  参考文献：
  名称：

  Electrochemical synthesis of dendritic diarylcarbenium ion pools

  摘要：

  Dendritic diarylcarbenium ion pools were synthesized by the low temperature electrochemical oxidation of the corresponding dendritic (diarylmethyl)trimethylsilanes, which were prepared by use of the iterative method consisting of electrochemical activation and Friedel Crafts type coupling. Time-course NMR studies revealed that thermal stability of dendritic diarylcarbenium ions depends both on the generation of the dendritic structure and on the para-substituents of the terminal phenyl groups. Dendritic diarylcarbenium ions up to the third generation exhibited high reactivity as a carbon electrophile. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.04.065
• 作为产物：
  描述：

  4,4'-二氟二苯甲烷 、 二苯甲基(三甲基)硅烷 在 三氟甲磺酸 、 tetrabutylammonium tetrafluoroborate 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 0.66h， 以79%的产率得到bis(4-bis(4-fluorophenyl)methylphenyl)methyl-trimethylsilane
  参考文献：
  名称：

  Electrochemical synthesis of dendritic diarylcarbenium ion pools

  摘要：

  Dendritic diarylcarbenium ion pools were synthesized by the low temperature electrochemical oxidation of the corresponding dendritic (diarylmethyl)trimethylsilanes, which were prepared by use of the iterative method consisting of electrochemical activation and Friedel Crafts type coupling. Time-course NMR studies revealed that thermal stability of dendritic diarylcarbenium ions depends both on the generation of the dendritic structure and on the para-substituents of the terminal phenyl groups. Dendritic diarylcarbenium ions up to the third generation exhibited high reactivity as a carbon electrophile. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.04.065

文献信息

• Iterative Molecular Assembly Based on the Cation-Pool Method. Convergent Synthesis of Dendritic Molecules
  作者：Toshiki Nokami、Kousuke Ohata、Masafumi Inoue、Hiroaki Tsuyama、Akito Shibuya、Kazuya Soga、Masayuki Okajima、Seiji Suga、Jun-ichi Yoshida

  DOI：10.1021/ja803487q

  日期：2008.8.1

  An iterative method for molecular assembly has been developed based on the cation-pool method using (trimethylsilyl)diphenylmethane as a building block. The silyl group works as both an activating group of the benzene ring in the Friedel-Crafts type reaction and an electroauxiliary in the subsequent low temperature anodic oxidation to generate dendritic diarylcarbenium ions, which were well characterized

  基于使用（三甲基甲硅烷基）二苯基甲烷作为构建块的阳离子池方法开发了一种用于分子组装的迭代方法。甲硅烷基在 Friedel-Crafts 型反应中既是苯环的活化基团，又是随后低温阳极氧化生成树枝状二芳基碳鎓离子的电助剂，低温 NMR 谱对其进行了很好的表征。通过重复序列实现了树枝状分子的会聚合成。