N,N'-bis(ethoxymethyl)piperazine | 14970-79-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: N,N'-bis(ethoxymethyl)piperazine
• 英文别名: N,N'-bis(ethyloxymethyl)piperazine；1,4-bis(ethoxymethyl)piperazine
• CAS: 14970-79-7
• 化学式: C₁₀H₂₂N₂O₂
• 分子量: 202.297
• InChiKey: NQTBOJCZVWSOIY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  24.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  环己氯化镁 、 N,N'-bis(ethoxymethyl)piperazine 生成 1,4-bis(cyclohexylmethyl)piperazine
  参考文献：
  名称：

  YANKEP E.; CHARLES G., TETRAHEDRON LETT., 28,(1987) N 4, 427-430

  摘要：

  DOI：
• 作为产物：
  描述：

  哌嗪 、 聚合甲醛 、 乙醇 在 potassium hydroxide 作用下， 以 乙醇 为溶剂， 以48%的产率得到N,N'-bis(ethoxymethyl)piperazine
  参考文献：
  名称：

  Synthesis of N,N′-bis(alkyloxymethyl)piperazines and examination of their antimicrobial properties

  摘要：

  Three-component condensation of piperazine with formaldehyde and aliphatic alcohols was employed for elucidating the possibility to synthesize N,N'-bis(alkyloxymethyl)piperazines. The structure of the resulting compounds was identified by 1H NMR spectroscopy. The antimicrobial properties of these compounds were examined with respect to microorganisms that infect cooling lubricants and lubricant oils.

  DOI：

  10.1134/s107042720905036x

文献信息

• Method for manufacturing stabilized polyacetal resin, stabilized polyacetal resin, stabilized polyacetal resin composition, and molded article of stabilized polyacetal resin
  申请人：Polyplastics Co., Ltd.

  公开号：EP1867667A1

  公开（公告）日：2007-12-19

  The present invention provides an agent to decompose unstable terminal group, which is effective in a small adding amount, which sufficiently decreases the quantity of residual unstable terminal group, and which generates very little limitation on the treatment method, the apparatus, and the use amount of the agent. Specifically, it provides a method for manufacturing stabilized polyacetal resin having the step of applying heat treatment to a polyacetal resin having an unstable terminal group in the presence of an agent to decompose the unstable terminal group, which agent is composed of a heterocyclic quaternary ammonium salt, thus decreasing the quantity of the unstable terminal group.

  本发明提供了一种分解不稳定末端基团的药剂，其添加量小，效果好，能充分减少残留的不稳定末端基团的数量，并且对处理方法、装置和药剂的使用量限制很小。具体地说，它提供了一种制造稳定聚缩醛树脂的方法，该方法的步骤是：在有药剂存在的情况下，对具有不稳定末端基团的聚缩醛树脂进行热处理，以分解不稳定末端基团，该药剂由杂环季铵盐组成，从而减少不稳定末端基团的数量。
• YANKEP E.; CHARLES G., TETRAHEDRON LETT., 28,(1987) N 4, 427-430
  作者：YANKEP E.、 CHARLES G.

  DOI：——

  日期：——
• Method for manufacturing stabilized polyacetal resin
  申请人：Polyplastics Co., Ltd.

  公开号：EP1867667B1

  公开（公告）日：2012-10-31
• Synthesis of N,N′-bis(alkyloxymethyl)piperazines and examination of their antimicrobial properties
  作者：V. M. Farzaliev、M. T. Abbasova、A. A. Ashurova、G. B. Babaeva、N. P. Ladokhina、Ya. M. Kerimova

  DOI：10.1134/s107042720905036x

  日期：2009.5

  Three-component condensation of piperazine with formaldehyde and aliphatic alcohols was employed for elucidating the possibility to synthesize N,N'-bis(alkyloxymethyl)piperazines. The structure of the resulting compounds was identified by 1H NMR spectroscopy. The antimicrobial properties of these compounds were examined with respect to microorganisms that infect cooling lubricants and lubricant oils.