5-ethyl-[1,3]dioxan-5-ylamine | 75237-75-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二恶烷
• 英文名称: 5-ethyl-[1,3]dioxan-5-ylamine
• 英文别名: 5-Aethyl-[1,3]dioxan-5-ylamin；5-ethyl-5-amino-1,3-dioxane；5-ethyl-1,3-dioxan-5-amine
• CAS: 75237-75-1
• 化学式: C₆H₁₃NO₂
• mdl: MFCD19204904
• 分子量: 131.175
• InChiKey: YQUSGTRZZJTRHB-UHFFFAOYSA-N

物化性质

• 沸点：
  181 °C
• 密度：
  1.0481 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  44.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  5-ethyl-[1,3]dioxan-5-ylamine 在 甲醇 、 镍 作用下， 80.0 ℃ 、9.81 MPa 条件下， 生成 (5-ethyl-[1,3]dioxan-5-yl)-methyl-amine
  参考文献：
  名称：

  Some Nitro and Amino Acetals Derived from Polyhydric Nitro Alcohols

  摘要：

  DOI：

  10.1021/ja01855a030
• 作为产物：
  描述：

  5-ethyl-5-nitro-[1,3]dioxane 在 甲醇 、 镍 作用下， 60.0~70.0 ℃ 、9.81 MPa 条件下， 生成 5-ethyl-[1,3]dioxan-5-ylamine
  参考文献：
  名称：

  Some Nitro and Amino Acetals Derived from Polyhydric Nitro Alcohols

  摘要：

  DOI：

  10.1021/ja01855a030

文献信息

• Haloalkylcarbonylamino-1,3-dioxane herbicide antidotes
  申请人：Stauffer Chemical Co.

  公开号：US04561876A1

  公开（公告）日：1985-12-31

  Herbicide antidote compounds having the formula: ##STR1## in which R is haloalkyl wherein halo is chlorine, bromine or iodine and the alkyl group has 1-4 carbon atoms, inclusive; R.sub.1 is selected from the group consisting of hydrogen; lower alkyl having 1-4 carbon atoms, inclusive; alkenyl having 2-4 carbon atoms, inclusive; and phenyl; R.sub.2 is selected from the group consisting of hydrogen and lower alkyl having 1-4 carbon atoms, inclusive; R.sub.3 is selected from the group consisting of hydrogen and lower alkyl having 1-4 carbon atoms, inclusive; R.sub.4 is selected from the group consisting of hydrogen and a nitro group; and either R.sub.3 is hydrogen or R.sub.4 is hydrogen.

  具有以下式子的除草剂解毒化合物：##STR1## 其中，R是卤代烷基，其中卤素是氯、溴或碘，烷基具有1-4个碳原子，包括；R.sub.1选自氢；具有1-4个碳原子的低烷基；具有2-4个碳原子的烯基；和苯基；R.sub.2选自氢和具有1-4个碳原子的低烷基；R.sub.3选自氢和具有1-4个碳原子的低烷基；R.sub.4选自氢和硝基基团；并且R.sub.3是氢或R.sub.4是氢。
• Polymeric quaternary ammonium salts possessing antimicrobial activity and methods for preparation and use thereof
  申请人：ANGUS CHEMICAL COMPANY

  公开号：EP0172656A2

  公开（公告）日：1986-02-26

  Quaternary ammonium salts exhibiting strong antimicrobial activity are disclosed along with the method of using them as antimicrobial agents. The salts having the formulas I or II: wherein R is C1-20 alkyl, C5-7 cycloalkyl or an aralkyl group, R' is methyl or ethyl, and X is a halogen, are prepared by the method comprising the steps of: (a) initially reacting 2-nitro-2-methyl-1,3-propanediol or 2-nitro-2-ethyl-1,3-propanediol or a mixture thereof and trioxane in a solvent containing an acid to obtain a first product; (b) reducing said first product by dissolving said first product in a solent and maintaining the resulting solution under ahydrogen atmosphere in the presence of a reduction catalyst to obtain a second product; (c) alkylating said second product by maintaining said second product under a hydrogen atmosphere in the presence of a formaldehyde solution, a solvent and an alkylation catalyst to obtain a third product; and (d) quaternizing said third product by reacting said third product with a halogenated hydrocarbon in the presence of a solvent to obtain quaternary ammonium salts.

  本研究公开了具有较强抗菌活性的季铵盐以及将其用作抗菌剂的方法。这些盐具有如下式子 I 或 II： 其中 R 是 C1-20 烷基、C5-7 环烷基或芳烷基，R' 是甲基或乙基，X 是卤素，其制备方法包括以下步骤： (a) 将 2-硝基-2-甲基-1,3-丙二醇或 2-硝基-2-乙基-1,3-丙二醇或其混合物与三氧 烷在含有酸的溶剂中进行初步反应，得到第一产物； (b) 在还原催化剂存在下，通过将所述第一产物溶解在溶剂中并将所得溶液保持在氢气环境下，还原所述第一产物，以获得第二产物； (c) 在甲醛溶液、溶剂和烷基化催化剂存在下，将所述第二产物保持在氢气环境下，使其烷基化，从而得到第三产物；以及 (d) 在溶剂存在下，使所述第三产物与卤代烃反应，对所述第三产物进行季铵化，得到季铵盐。
• Herbicide antidotes, production, use and compositions thereof
  申请人：STAUFFER CHEMICAL COMPANY

  公开号：EP0068709B1

  公开（公告）日：1985-10-30
• US4561876A
  申请人：——

  公开号：US4561876A

  公开（公告）日：1985-12-31
• US4567302A
  申请人：——

  公开号：US4567302A

  公开（公告）日：1986-01-28