methyl-bis-[2]naphthylmethyl-amine | 134274-69-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: methyl-bis-[2]naphthylmethyl-amine
• 英文别名: Methyl-bis-β-naphthylmethyl-amin；Methyl-bis-[2]naphthylmethyl-amin；N-methyl-1-naphthalen-2-yl-N-(naphthalen-2-ylmethyl)methanamine
• CAS: 134274-69-4
• 化学式: C₂₃H₂₁N
• 分子量: 311.426
• InChiKey: QMUNJWWRHIBJGY-UHFFFAOYSA-N

物化性质

• 熔点：
  87-88 °C
• 沸点：
  276-278 °C(Press: 15 Torr)
• 密度：
  1.132±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  萘-2-甲胺 、 2-萘甲醛 、 碘甲烷 以33%的产率得到methyl-bis-[2]naphthylmethyl-amine
  参考文献：
  名称：

  An improved two-resin method for the cleavage of tertiary amines from REM resin

  摘要：

  The use of polymer-bound guanidine 6b or polymer-bound phosphazene 6c significantly improve the yield of the Hofmann elimination step in the preparation of tertiary amines using REM resin, providing products with superior purities and free from contamination with trialkylammonium salts. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)01365-x

文献信息

• v. Braun; Moldaenke, Chemische Berichte, 1923, vol. 56, p. 2169
  作者：v. Braun、Moldaenke

  DOI：——

  日期：——
• An improved two-resin method for the cleavage of tertiary amines from REM resin
  作者：Carolina Alhambra、Julia Castro、Jose Luis Chiara、Esther Fernández、Alfonso Fernández-Mayoralas、José M Fiandor、Silvestre Garcı́a-Ochoa、Marı́a D Martı́n-Ortega

  DOI：10.1016/s0040-4039(01)01365-x

  日期：2001.9

  The use of polymer-bound guanidine 6b or polymer-bound phosphazene 6c significantly improve the yield of the Hofmann elimination step in the preparation of tertiary amines using REM resin, providing products with superior purities and free from contamination with trialkylammonium salts. (C) 2001 Elsevier Science Ltd. All rights reserved.