1,2-Dibrom-1-(4-bromphenyl)-2-phenylethan | 122212-99-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 1,2-Dibrom-1-(4-bromphenyl)-2-phenylethan
• 英文别名: 4,α,α'-tribromo-bibenzyl；4,α,α'-Tribrom-bibenzyl；1-Bromo-4-(1,2-dibromo-2-phenylethyl)benzene
• CAS: 122212-99-1
• 化学式: C₁₄H₁₁Br₃
• 分子量: 418.953
• InChiKey: ICIHKXGFFISSJQ-UHFFFAOYSA-N

物化性质

• 沸点：
  380.6±37.0 °C(Predicted)
• 密度：
  1.845±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,2-Dibrom-1-(4-bromphenyl)-2-phenylethan 在 氢氧化钾 作用下， 以 乙醇 为溶剂， 反应 24.0h， 以66%的产率得到1-溴-4-(苯基乙炔基)苯
  参考文献：
  名称：

  Hellwinkel, Dieter; Fritsch, Helmut, Chemische Berichte, 1989, vol. 122, p. 2351 - 2360

  摘要：

  DOI：
• 作为产物：
  描述：

  4-溴-反-二苯乙烯 在 溴 作用下， 以 乙醚 为溶剂， 以85%的产率得到1,2-Dibrom-1-(4-bromphenyl)-2-phenylethan
  参考文献：
  名称：

  Hellwinkel, Dieter; Fritsch, Helmut, Chemische Berichte, 1989, vol. 122, p. 2351 - 2360

  摘要：

  DOI：

文献信息

• Chemoselective and Stereoselective Debromination of Vicinal-Dibromides with Sodium Dithionite
  作者：Jitender M. Khurana、Arti Sehgal

  DOI：10.1080/00397919608003795

  日期：1996.10

  Abstract A simple and effcient procedure for the quantitative debromination of vic-dibromides has been reported with sodium dithionite at ambient temperature. These eliminations are chemoselective and also stereoselective.

  摘要 已经报道了一种在环境温度下用连二亚硫酸钠定量脱溴的简单有效的方法。这些消除是化学选择性的，也是立体选择性的。
• Alcohol Drinkers Overreport Their Energy Intake in the BIRNH Study: Evaluation by 24-Hour Urinary Excretion of Cations
  作者：Jianjun Zhang、Elisabeth HM Temme、Hugo Kesteloot

  DOI：10.1080/07315724.2001.10719060

  日期：2001.10

  Objective: Alcohol drinkers are generally considered to underreport their alcohol intake, but little is known about whether they correctly report their energy intake (EI). We assessed the validity of the reported energy intake of alcohol drinkers using the 24-hour urinary (U) excretion of potassium (K) and sodium (Na) as biomarkers.Methods: A total of 2,124 men and 1,998 women 25 to 74 years of age with a 24-hour urine collection. a random sample of the Belgian Interuniversity Research on Nutrition and Health (BIRNH), were studied. Dietary intake (D), including alcohol consumption, was assessed by a one-day food record, Basal metabolic rate (BMR) was predicted from age gender and weight. As a measure for the degree of reporting error. D-K/U-K, D-Na/U-Na, EI/U-K, Non-alcohol EI/U-Na (NAEI/U-Na), Ei/U-Na, EVU-creatinine and EI/BMR ratios were calculated and compared among non-, moderate and heavy drinkers in both genders.Results: El, NAEI and all seven ratios examined generally increased with the level of alcohol intake in both genders. After adjustment for age, body mass index, smoking and educational level, most ratios were significantly higher in moderate drinkers (p < 0.02 to p < 0.0001) and in heavy drinkers (all p < 0.0001) than in non-drinkers. These differences were most significant in male heavy drinkers. The exceptions were D-K/U-K. D-Na/U-Na and NAEI/U-Na in moderate and female heavy drinkers and EI/U-K in male moderate drinkers. The estimated amount of the overreporting of El by heavy drinkers was 27.8% in men and 13.7% in women.Conclusions: This study provides evidence that El and NAEI obtained from the BIRNH study was overreported among alcohol drinkers, especially among male heavy drinkers. It also indicates that El from alcohol replaced El from food.
• Hellwinkel, Dieter; Fritsch, Helmut, Chemische Berichte, 1989, vol. 122, p. 2351 - 2360
  作者：Hellwinkel, Dieter、Fritsch, Helmut

  DOI：——

  日期：——