1,2-diphenyl-2-methylbutane | 26613-38-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 1,2-diphenyl-2-methylbutane
• 英文别名: Benzene, 1,1'-(1-ethyl-1-methyl-1,2-ethanediyl)bis-；(2-methyl-1-phenylbutan-2-yl)benzene
• CAS: 26613-38-7
• 化学式: C₁₇H₂₀
• 分子量: 224.346
• InChiKey: KGBTVANMWBVNLP-UHFFFAOYSA-N

物化性质

• 沸点：
  138-140 °C(Press: 1.5 Torr)
• 密度：
  0.9718 g/cm3(Temp: 25 °C)

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  1-methyl-1-phenyl-n-propylamine 在 盐酸 、 sodium hydroxide 、 sodium dithionite 、 sodium nitrite 作用下， 生成 1,2-diphenyl-2-methylbutane
  参考文献：
  名称：

  Terashima,S. et al., Chemical and pharmaceutical bulletin, 1970, vol. 18, p. 1137 - 1144

  摘要：

  DOI：

文献信息

• Vanadium(II) complexes as efficient reagents for direct construction of asymmetric quaternary carbons from carbonyl compounds
  作者：Yasutaka Kataoka、Isamu Makihira、Hiroaki Akiyama、Kazuhide Tani

  DOI：10.1016/0040-4039(95)01299-w

  日期：1995.9

  Direct geminal diallylation of propiophenone with allyl bromide has been achieved in the presence of vanadium(II) species. By applying this method, direct construction of asymmetric quaternary carbons from propiophenone has been accomplished. Strong oxophilicity of the low-valent vanadium facilitated the deoxygenative reaction. The present reaction is characteristic of vanadium complexes.

  在钒（II）物种存在下，苯丙酮与烯丙基溴直接进行双键二烯丙基化反应。通过应用该方法，已经实现了由苯乙酮直接构建不对称季碳的方法。低价钒的强亲氧性促进了脱氧反应。本反应是钒配合物的特征。
• Direct construction of quaternary carbons from carbonyl compounds utilizing low-valent vanadium complexes
  作者：Yasutaka Kataoka、Isamu Makihira、Hiroaki Akiyama、Kazuhide Tani

  DOI：10.1016/s0040-4020(97)00632-7

  日期：1997.7

  Direct geminal diallylation of a carbonyl compound with allyl bromide has been achieved in the presence of a low-valent vanadium complex and zinc. The diallylation has been found to proceed stepwise and the two allyl groups were introduced successively. By applying this method, one-pot synthesis of asymmetric quaternary carbons has been accomplished. As the first alkylating reagent a combination of allyl bromide and zinc, a Grignard reagent, or an alkyllithium can be used. The second one should be the combination of a low-valent vanadium(II) complex and allyl bromide, benzyl bromide, or propargyl bromide. Strong oxophilicity of the low-valent vanadium facilitated the deoxygenative allylation. (C) 1997 Elsevier Science Ltd.
• Gelin,R. et al., Bulletin de la Societe Chimique de France, 1969, p. 4136 - 4147
  作者：Gelin,R. et al.

  DOI：——

  日期：——
• Decarbonylative diarylation reaction of N -tosylated α-amino acids
  作者：Mi Ra Seong、Hong Jung Lee、Jae Nyoung Kim

  DOI：10.1016/s0040-4039(98)01279-9

  日期：1998.8

  The reaction of various N-tosylated alpha-amino acids with arenes in the presence of sulfuric acid afforded the corresponding diarylated derivatives in moderate yields, which were generated via decarbonylative arylation followed by Friedel-Craffs reaction of the generated tosylamide derivatives. (C) 1998 Elsevier Science Ltd. All rights reserved.
• OKADA, TAKASHI;NAMBA, OSAMU;KUBO, CHIKAKO;NISHIYAMA, YUTAKA;HAMANAKA, SAW+, CHEM. EXPRESS., 5,(1990) N, C. 293-296
  作者：OKADA, TAKASHI、NAMBA, OSAMU、KUBO, CHIKAKO、NISHIYAMA, YUTAKA、HAMANAKA, SAW+

  DOI：——

  日期：——