2,4-diethylpiperidine | 116435-88-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 2,4-diethylpiperidine
• 英文别名: 2,4-diethyl-piperidine；2,4-Diaethyl-piperidin
• CAS: 116435-88-2
• 化学式: C₉H₁₉N
• 分子量: 141.257
• InChiKey: WAYNDWSLNIRTJK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2,4-二乙基吡啶二羧酸 在 硫酸 、 sodium ethanolate 、 dioxide titanium 作用下， 以 乙酸乙酯 为溶剂， 反应 16.0h， 生成 2,4-diethylpiperidine
  参考文献：
  名称：

  Attia, A.; El-Salam, O. I. Abd; Youssef, T. E., Egyptian Journal of Chemistry, 2000, vol. 43, # 5, p. 351 - 362

  摘要：

  DOI：

文献信息

• Process for producing catalyst for alpha -olefin polymerization and process for producing alpha -olefin polymer
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20030134992A1

  公开（公告）日：2003-07-17

  There are provided a process for producing a catalyst for &agr;-olefin polymerization, which comprises the step of contacting (1) a solid catalyst component having Ti, Mg and a halogen as essential components, (2) an organoaluminum compound and (3) a compound having a —C—O—C—O—C— bond group in a closed ring structure with one another; and a process for producing an &agr;-olefin polymer, which comprises the step of homopolymerizing or copolymerizing an &agr;-olefin in the presence of a catalyst for &agr;-olefin polymerization produced by the above process.

  提供了一种生产烯烃聚合催化剂的工艺，该工艺包括以下步骤：(1)以 Ti、Mg 和卤素为主要成分的固体催化剂组分，(2)有机铝化合物和(3)在闭环结构中具有-C-O-C-O-C-键基的化合物相互接触；以及一种生产&agr;-烯烃聚合物的工艺，该工艺包括在上述工艺生产的&agr;-烯烃聚合催化剂存在下均聚或共聚&agr;-烯烃的步骤。
• Process for producing catalyst for alpha-olefin polymerization and process for producing alpha-olefin polymer
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20040092679A1

  公开（公告）日：2004-05-13

  There are provided a process for producing a catalyst for &agr;-olefin polymerization, which comprises the step of contacting (1) a solid catalyst component having Ti, Mg and a halogen as essential components, (2) an organoaluminum compound and (3) a compound having a —C—O—C—O—C— bond group in a closed ring structure with one another; and a process for producing an &agr;-olefin polymer, which comprises the step of homopolymerizing or copolymerizing an &agr;-olefin in the presence of a catalyst for &agr;-olefin polymerization produced by the above process.

  提供了一种生产烯烃聚合催化剂的工艺，该工艺包括以下步骤：(1)以 Ti、Mg 和卤素为主要成分的固体催化剂组分，(2)有机铝化合物和(3)在闭环结构中具有-C-O-C-O-C-键基的化合物相互接触；以及一种生产&agr;-烯烃聚合物的工艺，该工艺包括在上述工艺生产的&agr;-烯烃聚合催化剂存在下均聚或共聚&agr;-烯烃的步骤。
• Ladenburg, Justus Liebigs Annalen der Chemie, 1888, vol. 247, p. 97
  作者：Ladenburg

  DOI：——

  日期：——
• BIARYL DERIVATIVE, PREPARATION METHOD THEREOF AND PHARMACEUTICAL APPLICATION THEREOF
  申请人：ABBISKO THERAPEUTICS CO., LTD.

  公开号：US20210032270A1

  公开（公告）日：2021-02-04

  Disclosed are a biaryl derivative having a structure represented by Formula (I) and inhibitory activity against PD-1/PD-L1 interaction, a preparation method thereof, and a pharmaceutical application thereof. The series of compounds of the can be widely applied to the preparation of a medicament for preventing and/or treating cancer or tumors, immune-related diseases and disorders, contagious diseases, infectious diseases or metabolic diseases that are mediated by a PD-1/PD-L1 signaling pathway, and shows promise for the development of a new generation of PD-1/PD-L1 inhibitors.
• US4334073A
  申请人：——

  公开号：US4334073A

  公开（公告）日：1982-06-08