| 1067675-68-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• CAS: 1067675-68-6；886997-76-8
• 化学式: C₄₆H₂₇IO₆P₂Pd
• 分子量: 970.989
• InChiKey: AJCUXHDVSQZVCO-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  、 silver trifluoroacetate 以 二氯甲烷 为溶剂， 以99%的产率得到
  参考文献：
  名称：

  Synthesis of new chiral pincer-complex catalysts for asymmetric allylation of sulfonimines

  摘要：

  Four new chiral pincer-complexes were prepared based on coupling of BINOL and TADDOL moieties with iodoresorcinol followed by oxidative addition of palladium(0). The X-ray analysis of complex 5a revealed that the BINOL rings form a well-defined chiral pocket around the palladium atom. This chiral environment can be further modified by gamma-substitution of the BINOL rings. Preliminary studies for electrophilic allylation of sulfonimine 2 with allylstannane revealed that the presented chiral complexes are promising asymmetric catalysts for preparation of chiral homoallyl amines. The best result was achieved employing catalytic amounts of gamma-Me BINOL complex 6 affording homoallyl amine 4 with 59% ee and 74% isolated yield. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2005.06.059
• 作为产物：
  描述：

  tris(dibenzylideneacetone)dipalladium (0) 、 C₆H₃I(O₃PC₂₀H₁₂)2 以 甲苯 为溶剂， 以89%的产率得到
  参考文献：
  名称：

  Synthesis of new chiral pincer-complex catalysts for asymmetric allylation of sulfonimines

  摘要：

  Four new chiral pincer-complexes were prepared based on coupling of BINOL and TADDOL moieties with iodoresorcinol followed by oxidative addition of palladium(0). The X-ray analysis of complex 5a revealed that the BINOL rings form a well-defined chiral pocket around the palladium atom. This chiral environment can be further modified by gamma-substitution of the BINOL rings. Preliminary studies for electrophilic allylation of sulfonimine 2 with allylstannane revealed that the presented chiral complexes are promising asymmetric catalysts for preparation of chiral homoallyl amines. The best result was achieved employing catalytic amounts of gamma-Me BINOL complex 6 affording homoallyl amine 4 with 59% ee and 74% isolated yield. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2005.06.059