1,3-bis(triphenylmethoxy)-2-propanone | 688319-39-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: 1,3-bis(triphenylmethoxy)-2-propanone
• 英文别名: 1,3-bis-trityloxy-acetone；1.3-Bis-triphenylmethoxy-2-oxo-propan；1.3-Bis-triphenylmethoxy-aceton；1,3-Bis-trityloxy-aceton；1.3-Ditrityloxy-aceton；1,3-ditrityloxypropan-2-one
• CAS: 688319-39-3
• 化学式: C₄₁H₃₄O₃
• 分子量: 574.719
• InChiKey: CFDPWRUFKWOEEJ-UHFFFAOYSA-N

物化性质

• 熔点：
  184 °C(Solv: acetone (67-64-1); water (7732-18-5))
• 沸点：
  698.0±50.0 °C(Predicted)
• 密度：
  1.157±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.57
• 重原子数：
  44.0
• 可旋转键数：
  12.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  35.53
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  1,3-bis(triphenylmethoxy)-2-propanone 、 2,4-二硝基苯肼 生成 1,3-bis-trityloxy-acetone-(2,4-dinitro-phenylhydrazone)
  参考文献：
  名称：

  Conceptual classroom environment - a system view of learning

  摘要：

  This paper examines the relations between changes in the beliefs of an individual student and the distribution of beliefs in a classroom. The distribution of beliefs among students is termed here 'conceptual environment'. Based on social views of learning, we suggest that conceptual environment is an indicator of the conceptual tension in a group.We show that conceptual change of individuals does not necessarily result in changes in the classroom conceptual environment. Conceptual change is normally viewed as a personal process. We look at the relations between individual conceptual change (a microscopic view) and total classroom conceptual change (a macroscopic, system view).We study changes in students' ideas of a food chain. Then we look for underlying ontological beliefs that may explain students' ideas, and examine changes in students' responses prior and consequent to the instruction sessions. Classroom concepts of a food chain reflect an underlying set of beliefs of a mechanistic nature. For instance the metaphor of a 'chain of beads' is employed to explain the relations among elements of a food chain.Though more than half of the students changed their responses, ontological beliefs were hardly changed. Changes in students' responses apparently cancelled each other, thus from the classroom point of view, only a minor change was identified in the overall conceptual environment. The social-conceptual tension involved in conceptual change is not necessarily changed.

  DOI：

  10.1080/095006901300172458
• 作为产物：
  描述：

  1,3-二(三苯甲氧基)丙-2-醇 在 碳酸氢钠 4-acetylamino-2,2,6,6-tetramethylpiperidine-N-oxyl 、 sodium hypochlorite 、 sodium bromide 作用下， 以 二氯甲烷 为溶剂， 反应 0.5h， 以93%的产率得到1,3-bis(triphenylmethoxy)-2-propanone
  参考文献：
  名称：

  立体地阻碍了三酰基甘油类似物作为人类消化脂肪酶的有效抑制剂。

  摘要：

  已经开发了新型的人类消化脂肪酶抑制剂。合成了各种基于2-甲基和2-丁基甘油和/或2-甲基脂肪酸的空间位阻三酰基甘油。通过记录三酰基甘油类似物的表面压力/分子面积等温线，测试了它们在空气/水界面形成稳定单分子膜的能力。通过使用具有1,2-二癸酸酯混合膜的单层技术研究了空间受阻的三酰基甘油类似物对人胰腺和胃脂肪酶的抑制作用，其中每种抑制剂的含量各不相同。在甘油主链2位上含有丁基或在甘油2位上均含有甲基的三油精类似物，每个油酸残基的α位是有效的抑制剂。这导致0.003摩尔分数的HPL活性降低了50％。

  DOI：

  10.1002/chem.200305573

文献信息

• Heyns; Stein, Justus Liebigs Annalen der Chemie, 1947, vol. 558, p. 194,197
  作者：Heyns、Stein

  DOI：——

  日期：——
• Zur Kenntnis des alkalischen Zuckerabbaues
  作者：E. Waldmann、V. Prey

  DOI：10.1007/bf00905123

  日期：1951.9