(2Z)-3-ethyl-2-[2-[(3-ethyl-5-phenyl-1,3-benzoxazol-3-ium-2-yl)methylidene]butylidene]-5-phenyl-1,3-benzoxazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶唑类
• 英文名称: (2Z)-3-ethyl-2-[2-[(3-ethyl-5-phenyl-1,3-benzoxazol-3-ium-2-yl)methylidene]butylidene]-5-phenyl-1,3-benzoxazole
• 化学式: C35H33N2O2+
• 分子量: 513.6
• InChiKey: GJDCORVLYUCREY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.5
• 重原子数：
  39
• 可旋转键数：
  7
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] CANCER CELL INHIBITORY DRUG AND CANCER STEM-CELL DETECTION PROBE<br/>[FR] MÉDICAMENT INHIBITEUR DE CELLULES CANCÉREUSES ET SONDE DE DÉTECTION DE CELLULES SOUCHES CANCÉREUSES
  申请人：CANON KK

  公开号：WO2014065439A1

  公开（公告）日：2014-05-01

  An object of the present invention is to provide a cancer cell inhibitory drug, particularly a cancer stem-cell inhibitory drug, or a cancer stem-cell detection probe. The present invention provides a cancer cell inhibitory drug comprising at least one compound represented by general formula (1) as an active ingredient.

  本发明的目的是提供一种癌细胞抑制药物，特别是一种癌干细胞抑制药物，或一种癌干细胞检测探针。本发明提供了一种包含至少一种以通式（1）表示的化合物作为活性成分的癌细胞抑制药物。
• Hologram Recording Material
  申请人：Kawaguchi Yoshihide

  公开号：US20080305404A1

  公开（公告）日：2008-12-11

  The present invention provides a hologram recording material which can modulate its refractive index effectively with visible light laser and is excellent also in transparency after this modulation. The present invention relates to a hologram recording material comprising a polymer (A) having a radically polymerizable side chain vinyl group in the molecule thereof, said polymer (A) being a polymer of monomers comprising as an essential component an acryl-vinyl monomer represented by the following formula (1): CH 2 ═C(R 1 )C(═O)O—R 2 ═CH 2 (1) wherein R 1 represents a hydrogen atom or methyl group, and R 2 represents a saturated or unsaturated hydrocarbon group having 1 to 20 carbon atoms, which may contain hetero atoms or halogen atoms in the molecule thereof; and a photopolymerization initiation source (B) which generates an active seed by visible light, and particularly relates to a hologram recording material having the aforementioned constitution in which the aforementioned photopolymerization initiation source (B) is a photopolymerization initiator which absorbs visible light to generate an active seed or a mixture of visible light-sensitizing dye and photopolymerization initiator.
• OPTICAL RECORDING MEDIA
  申请人：Matsui Fumio

  公开号：US20090081401A1

  公开（公告）日：2009-03-26

  An optical recording medium which comprises a substrate and a recording layer provided on the substrate by using an organic dye compound having absorption maximum in a region with wavelengths longer than that of a writing light used, and which records information by allowing to irradiate the recording layer with the writing light to act on the organic dye compound to form a pit on the substrate.
• PROBE FOR A HAIR CELL, AND LABELLING METHOD FOR A HAIR CELL USING THE PROBE FOR A HAIR CELL
  申请人：Nomoto Tsuyoshi

  公开号：US20100166663A1

  公开（公告）日：2010-07-01

  Provided are a novel probe for a hair cell for clearly identifying various conditions of a hair cell, and a labelling method for a hair cell using the probe for a hair cell, more particularly, a probe for a hair cell containing, as an active agent, at least one kind selected from staining compounds represented by one of the general formulae (I) and (II), and a labelling method for a hair cell using the probe for a hair cell.
• LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD
  申请人：Watanabe Kohei

  公开号：US20110236310A1

  公开（公告）日：2011-09-29

  The invention provides a labeling composition for an intraocular tissue of a living individual, which specifically labels the intraocular tissue without need of an invasive operation such as exposure of an ocular tissue or injection of a staining agent into the ocular tissue or a nerve tissue linking to the ocular tissue, a method of noninvasively labeling an intraocular tissue of a living individual, and a screening method using the labeling composition for the intraocular tissues. The composition contains a compound capable of labeling at least a photoreceptor cell layer of a retina, wherein the compound is a staining compound having a particular structure as a partial structure thereof.