(4R)-4,5-dimethylhexan-1-amine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (4R)-4,5-dimethylhexan-1-amine
• 化学式: C₈H₁₉N
• 分子量: 129.24
• InChiKey: HTQJGGGPLKSZKR-MRVPVSSYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• THERMOPLASTIC RESIN COMPOSITION, AND LAMINATE USING SAME
  申请人：Riken Technos Corporation

  公开号：EP3508530A1

  公开（公告）日：2019-07-10

  [Technical Problem] There are provided a thermoplastic resin composition capable of bonding a cyclic polyolefin-based polymer and an ethylene-vinyl alcohol copolymer with sufficient strength and to provide a laminate using the same. [Solution of Problem] Thermoplastic resin composition comprising: (A) 100 parts by mass of a thermoplastic resin; (B) 0.05 to 5 parts by mass of one or more selected from the group consisting of an unsaturated carboxylic acid and a derivative of an unsaturated carboxylic acid; and (C) 0.01 to 3 parts by mass of an organic peroxide, said thermoplastic resin (A) comprising: (a1) 10 to 90 % by mass of a cyclic polyolefin-based polymer; and (a2) 90 to10 % by mass of one or more selected from the group consisting of a copolymer of an aromatic vinyl compound and a conjugated diene compound and a hydrogenated product thereof except for a hydrogenated product of a block copolymer of a polymer block mainly composed of an aromatic vinyl compound and a random copolymer block composed of a conjugated diene compound and an aromatic vinyl compound, wherein the total of the components (a1) and (a2) is 100 % by mass.

  [技术问题］ 提供一种热塑性树脂组合物，该组合物能够以足够的强度粘合环状聚烯烃基聚合物和乙烯-乙烯醇共聚物，并提供使用该组合物的层压板。 [问题解决方案］ 热塑性树脂组合物，包括：(A) 100 份热塑性树脂；(B) 0.05 至 5 份不饱和羧酸和不饱和羧酸衍生物中的一种或多种；以及 (C) 0.以质量份数计，0.01 至 3 份有机过氧化物，所述热塑性树脂 (A) 包括(a1) 10%至 90%（质量百分比）的环状聚烯烃基聚合物；以及 (a2) 90%至 10%（质量百分比）的一种或多种选自芳香族乙烯基化合物和共轭二 烯化合物的共聚物及其氢化产物（主要由芳香族乙烯基化合物组成的聚合物嵌段 和由共轭二烯化合物和芳香族乙烯基化合物组成的无规共聚物嵌段的氢化产物除 外），其中组分 (a1) 和 (a2) 的总质量百分比为 100%。
• Bouvardin derivatives and therapeutic uses thereof
  申请人：The Regents of the University of Colorado, a body corporate

  公开号：US10259846B2

  公开（公告）日：2019-04-16

  The present invention is directed at bouvardin analogs arid related compounds for the treatment of disorders including cancer. Provided herein are bouvardin analogs and related compounds, pharmaceutical compositions and kits comprising at least one bouvardin analog or related compound, and methods for treating disorders including cancer. In some aspects the compounds inhibit translation elongation at the ribosome. The compounds are used in combination with radiation therapy or with known chemotherapeutic compositions.

  本发明针对用于治疗包括癌症在内的疾病的毛花苷类似物和相关化合物。本发明提供了毛花苷类似物和相关化合物、包含至少一种毛花苷类似物或相关化合物的药物组合物和试剂盒，以及治疗包括癌症在内的疾病的方法。在某些方面，这些化合物可抑制核糖体的翻译延伸。这些化合物可与放射治疗或已知的化疗组合物结合使用。
• Aesthetic method of biological structure treatment by magnetic field
  申请人：BTL Healthcare Technologies A.S.

  公开号：US11253717B2

  公开（公告）日：2022-02-22

  In combined methods for treating a patient using time-varying magnetic field, treatment methods combine various approaches for aesthetic treatment. A magnetic field generating device is placed proximate to a body region of the patient. The magnetic field generating device generates a time-varying magnetic field with a magnetic flux density in a range of 0.5 to 7 Tesla. The time-varying magnetic field is applied to the body region of the patient in order to cause a contraction of a muscle within the body region. A second therapy may be used by applying one or more of optical waves, radio frequency waves, mechanical waves, negative or positive pressure or heat to the body region of the patient.

  在使用时变磁场治疗患者的组合方法中，治疗方法结合了各种美容治疗方法。磁场发生装置靠近患者的身体区域。磁场发生装置产生的时变磁场的磁通密度范围为 0.5 到 7 特斯拉。将时变磁场施加到患者的身体区域，以引起身体区域内肌肉的收缩。第二种疗法可通过向患者身体区域施加光波、射频波、机械波、负压或正压或热量中的一种或多种。
• BOUVARDIN DERIVATIVES AND THERAPEUTIC USES THEREOF
  申请人：The Regents of the University of Colorado, a body corporate

  公开号：US20170218025A1

  公开（公告）日：2017-08-03

  The present invention is directed at bouvardin analogs arid related compounds for the treatment of disorders including cancer. Provided herein are bouvardin analogs and related compounds, pharmaceutical compositions and kits comprising at least one bouvardin analog or related compound, and methods for treating disorders including cancer. In some aspects the compounds inhibit translation elongation at the ribosome. The compounds are used in combination with radiation therapy or with known chemotherapeutic compositions.
• [8-(PHENYLSULFONYL)-3,8-DIAZABICYCLO[3.2.1]OCT-3-YL](1H-1,2,3-TRIAZOL-4-YL)METHANONES
  申请人：BAYER PHARMA AKTIENGESELLSCHAFT

  公开号：US20170342082A1

  公开（公告）日：2017-11-30

  The present invention covers [8-(phenylsulfonyl)-3,8-diazabicyclo[3.2.1]oct-3-yl](1H-1,2,3-triazol-4-yl)methanone compounds of general formula (I): in which R 1 , R 2 , R 3 , R 4 and R 5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of disorders, in particular of gynecological disorders, hyperproliferative disorders, metabolic disorders, or inflammatory disorders as a sole agent or in combination with other active ingredients.