申请人:Ratner Buddy D.
公开号:US20140086995A1
公开(公告)日:2014-03-27
Compositions and methods for localized delivery of a therapeutic agent to a biological tissue over time. The composition includes a temperature-responsive polymer and one or more microspheres, each having degradation rate different from the other, and each comprising a therapeutic agent. In the method, the composition is applied to a biological tissue and forms a gel that adheres to the tissue.