(2S)-1-(2-ethylphenoxy)-1-[[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]amino]propan-2-ol

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: (2S)-1-(2-ethylphenoxy)-1-[[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]amino]propan-2-ol
• 化学式: C₂₁H₂₇NO₂
• 分子量: 325.4
• InChiKey: JNENNZJIVCGEKK-BGNMZJEESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  41.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• [EN] METHODS AND PRODUCTS FOR PREVENTING AND/OR TREATING A STRESS INDUCED CARDIOMYOPATHY<br/>[FR] MÉTHODES ET PRODUITS DE PRÉVENTION ET/OU DE TRAITEMMENT D'UNE CARDIOMYOPATHIE INDUITE PAR LE STRESS
  申请人：ADELAIDE RES & INNOVATION PTY

  公开号：WO2014063189A1

  公开（公告）日：2014-05-01

  The present disclosure relates to methods and products for preventing and/or treating a stress- induced cardiomyopathy. Certain embodiments of the present disclosure provide a method of preventing and/or treating a stress-induced cardiomyopathy in a subject, the method comprising administering to the subject a therapeutically effective amount of one or more of the following agents: a peroxynitrite inhibitor; an inhibitor of peroxynitrite synthesis; an inhibitor of peroxynitrite associated signalling; an inhibitor of peroxynitrite-induced DNA damage; a Tx NIP inhibitor; a beta 2 adrenoceptor antagonist; and a beta 3 adrenoceptor antagonist; thereby preventing and/or treating the stress-induced cardiomyopathy in the subject.