tert-butyl N-[(1R,2R)-2-hydroxy-7-[(3-methoxybenzoyl)amino]-1,2,3,4-tetrahydronaphthalen-1-yl]carbamate

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: tert-butyl N-[(1R,2R)-2-hydroxy-7-[(3-methoxybenzoyl)amino]-1,2,3,4-tetrahydronaphthalen-1-yl]carbamate
• 化学式: C₂₃H₂₈N₂O₅
• 分子量: 412.5
• InChiKey: JJODLJJQGITBJI-WOJBJXKFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  96.9
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• US20140342406A1
  申请人：——

  公开号：US20140342406A1

  公开（公告）日：2014-11-20
• ANTIBODIES TO ION CHANNELS
  申请人：UCB BIOPHARMA SPRL

  公开号：US20150203571A1

  公开（公告）日：2015-07-23

  An anti-E1 ion channel antibody or binding fragment thereof, pharmaceutical compositions comprising said antibodies, use of the antibodies and compositions comprising the same, in treatment, for example in the treatment/modulation of pain and processes for generating and preparing said antibodies.
• FUNCTION MODIFYING NAv1.7 ANTIBODIES
  申请人：UCB BIOPHARMA SPRL

  公开号：US20150232553A1

  公开（公告）日：2015-08-20

  A Na v 1.7 binding entity that after binding functionally modifies the activity of the ion channel, in particular an anti-Na v 1.7 antibody or binding fragment thereof, pharmaceutical compositions comprising said antibodies, use of the antibodies and compositions comprising the same, in treatment, for example in the treatment/modulation of pain and processes for generating and preparing said antibodies.
• METHODS OF TREATING PAIN USING FUNCTION MODIFYING NAv1.7 ANTIBODIES
  申请人：UCB Biopharma SPRL

  公开号：US20160222107A1

  公开（公告）日：2016-08-04

  A Na v 1.7 binding entity that after binding functionally modifies the activity of the ion channel, in particular an anti-Na v 1.7 antibody or binding fragment thereof, pharmaceutical compositions comprising said antibodies, use of the antibodies and compositions comprising the same, in treatment, for example in the treatment/modulation of pain and processes for generating and preparing said antibodies.
• US8734798B2
  申请人：——

  公开号：US8734798B2

  公开（公告）日：2014-05-27