(E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]non-7-enamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]non-7-enamide
• 化学式: C₁₇H₂₅NO₃
• 分子量: 291.4
• InChiKey: IFHWJUBDUIVTHA-ONEGZZNKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  21
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  58.6
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Cough Reducing Product
  申请人：Millqvist Eva

  公开号：US20140171511A1

  公开（公告）日：2014-06-19

  The present invention relates to a product comprising capsaicin or a capsaicinoid for use in the treatment of cough, in particular chronic persistent unexplained cough or increased cough reflex sensitivity. More precisely, the invention concerns oral formulations for reducing and relieving coughing from other irritants than capsaicin itself. The capsaicin formulations are stated to down-regulate coughing following a regular consumption. Said products can also be used in the treatment of rhinitis and other conditions known to have cough symptoms.