10-N,10-N,31-N,31-N-tetramethyl-20-[(1S,2R)-2-octylcyclopropyl]-19-[(1S,2S)-2-[[(1R,2R)-2-pentylcyclopropyl]methyl]cyclopropyl]tetracontane-10,31-diamine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 10-N,10-N,31-N,31-N-tetramethyl-20-[(1S,2R)-2-octylcyclopropyl]-19-[(1S,2S)-2-[[(1R,2R)-2-pentylcyclopropyl]methyl]cyclopropyl]tetracontane-10,31-diamine
• 化学式: C₆₇H₁₃₂N₂
• 分子量: 965.8
• InChiKey: OLDQSCSYTDYEQO-PFFAFTNDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  29
• 重原子数：
  69
• 可旋转键数：
  54
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• MODIFIED POLYNUCLEOTIDES FOR TREATING DOLICHYL-PHOSPHATE (UDP-N-ACETYLGLUCOSAMINE) N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE 1 (GLCNAC-1-P TRANSFERASE) PROTEIN DEFICIENCY
  申请人：Moderna Therapeutics, Inc.

  公开号：US20140179771A1

  公开（公告）日：2014-06-26

  The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
• MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF COSMETIC PROTEINS AND PEPTIDES
  申请人：ModernaTX, Inc.

  公开号：US20180360995A1

  公开（公告）日：2018-12-20

  The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of cosmetic polynucleotides, cosmetic primary transcripts and cosmetic mmRNA molecules.