[(8S,9S,10R,13S,14S,17S)-17-acetyl-10,13,16-trimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-7-yl] benzoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: [(8S,9S,10R,13S,14S,17S)-17-acetyl-10,13,16-trimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-7-yl] benzoate
• 化学式: C₂₉H₃₄O₄
• 分子量: 446.6
• InChiKey: ISAULIYZWNYYAM-OPSQJHKFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  33
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  60.4
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] FORMULATIONS AND METHODS FOR THEIR USE IN TREATMENT OF NEUROPATHOLOGY AND NEURODEGENERATION AS A RESULT OF TRAUMATIC INJURY<br/>[FR] FORMULATIONS ET PROCÉDÉS DESTINÉS À ÊTRE UTILISÉS DANS LE TRAITEMENT D'UNE NEUROPATHOLOGIE ET D'UNE NEURODÉGÉNÉRESCENCE EN RÉSULTAT D'UNE LÉSION TRAUMATIQUE
  申请人：SAPNA LIFE SCIENCES CORP

  公开号：WO2014107794A1

  公开（公告）日：2014-07-17

  The presently disclosed invention and particular invention embodiments relate to formulations, methods, procedures, and combinations thereof for treating numerous types of trauma-induced and other neurological disorders and injuries, such as but not exclusive to brain injury, central nervous system ischemia, spinal cord injury, enteric nervous system injury and peripheral nerve injury. The formulations of the present invention comprising two, three or four biologically active compounds selected from A. at least one biologically active compound selected from anticonvulsants and antiepileptics; B. at least one biologically active compound selected from neurosteroids and neuroactive steroids; C. at least one biologically active compound selected from NK-1 receptor antagonists; and D. at least one biologically active compound selected from lithium containing and lithium-related compounds.