6-Propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 6-Propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
• 英文别名: 6-propyl-5,7-dihydro-4H-1,3-benzothiazole-2,6-diamine
• 化学式: C₁₀H₁₇N₃S
• 分子量: 211.33
• InChiKey: JUITYOOTUPGZCW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  93.2
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Novel D3 Dopamine Receptor Agonists to Treat Dyskinesia in Parkinson's Disease
  申请人：University of Medicine and Dentistry New Jersey Medical School

  公开号：US20140228380A1

  公开（公告）日：2014-08-14

  The present invention provides a method of inhibiting, suppressing or preventing levodopa-induced dyskinesia in a patient suffering from Parkinson's Disease, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention. The present invention further provides a method of inhibiting, suppressing or preventing Parkinson's Disease in a patient, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention.
• US9675565B2
  申请人：——

  公开号：US9675565B2

  公开（公告）日：2017-06-13