(4-methylphenyl) [(2S)-oxiran-2-yl]methyl sulfate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机硫酸及其衍生物
• 英文名称: (4-methylphenyl) [(2S)-oxiran-2-yl]methyl sulfate
• 化学式: C₁₀H₁₂O₅S
• 分子量: 244.27
• InChiKey: CXOGMLRTDRPCGT-JTQLQIEISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  73.5
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• BISPHENOL ETHER COMPOUNDS WITH NOVEL BRIDGING GROUPS AND METHODS FOR THEIR USE
  申请人：British Columbia Cancer Agency Branch

  公开号：US20150010469A1

  公开（公告）日：2015-01-08

  Compounds having a structure of Formula I: or a pharmaceutically acceptable salt, tautomer, stereoisomer or deuterated analogue thereof, wherein X, R, R 1 , R 2 , R 3 , R 4 , M 1 , M 2 , L 1 , L 2 , J 1 , J 2 , a 1 , a 2 , b 1 and b 2 are as defined herein, are provided. Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.

  本文提供具有如下式I结构的化合物或其药学上可接受的盐、互变异构体、立体异构体或氘代类似物，其中X、R、R1、R2、R3、R4、M1、M2、L1、L2、J1、J2、a1、a2、b1和b2的定义如本文所述。本文还提供了这些化合物用于治疗各种症状的用途，包括前列腺癌以及涉及这些化合物的治疗方法。
• BISPHENOL COMPOUNDS AND METHODS FOR THEIR USE
  申请人：Andersen Raymond John

  公开号：US20140248263A1

  公开（公告）日：2014-09-04

  Compounds having a structure of Formula I: wherein G, a, Q, L 2 , R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are as defined herein are provided. Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.

  提供具有公式I结构的化合物，其中G，a，Q，L2，R1，R2，R3，R4，R5和R6的定义如本文所述。提供了这种化合物用于治疗各种适应症，包括前列腺癌以及涉及这种化合物的治疗方法。