(6-methoxy-2,5-dimethyl-3,4-dihydro-[1]naphthyl)-acetic acid | 679835-60-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: (6-methoxy-2,5-dimethyl-3,4-dihydro-[1]naphthyl)-acetic acid
• 英文别名: (6-Methoxy-2,5-dimethyl-3,4-dihydro-[1]naphthyl)-essigsaeure；2-(6-Methoxy-2,5-dimethyl-3,4-dihydronaphthalen-1-yl)acetic acid；2-(6-methoxy-2,5-dimethyl-3,4-dihydronaphthalen-1-yl)acetic acid
• CAS: 679835-60-0
• 化学式: C₁₅H₁₈O₃
• 分子量: 246.306
• InChiKey: MNDKUMCRLWKMBC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (6-methoxy-2,5-dimethyl-3,4-dihydro-[1]naphthyl)-acetic acid 在 Pd/SrCO₃ 、 乙酸乙酯 、 丙酮 作用下， 生成 (6-methoxy-2,5-dimethyl-1,2,3,4-tetrahydro-[1]naphthyl)-acetic acid
  参考文献：
  名称：

  Experimental laser destruction of trigeminal sensory root

  摘要：

  The possibility of local laser destruction of the trigeminal sensory root by a puncture technique is demonstrated. A fibrous scar was formed on a limited area of the trigeminal root. There were no signs of axonal regeneration, posttraumatic neuroma, or considerable changes in the Meekel sinus.

  DOI：

  10.1007/bf02434888
• 作为产物：
  描述：

  (1-hydroxy-6-methoxy-2-methoxycarbonyl-2,5-dimethyl-1,2,3,4-tetrahydro-[1]naphthyl)-acetic acid methyl ester 在 盐酸 、 calcium chloride 、 苯 作用下， 60.0 ℃ 、2.45 MPa 条件下， 生成 (6-methoxy-2,5-dimethyl-3,4-dihydro-[1]naphthyl)-acetic acid
  参考文献：
  名称：

  Experimental laser destruction of trigeminal sensory root

  摘要：

  The possibility of local laser destruction of the trigeminal sensory root by a puncture technique is demonstrated. A fibrous scar was formed on a limited area of the trigeminal root. There were no signs of axonal regeneration, posttraumatic neuroma, or considerable changes in the Meekel sinus.

  DOI：

  10.1007/bf02434888

文献信息

• Experimental laser destruction of trigeminal sensory root
  作者：R. U. Giniatullin、A. I. Kozel'、S. T. Ismagilova

  DOI：10.1007/bf02434888

  日期：2000.6

  The possibility of local laser destruction of the trigeminal sensory root by a puncture technique is demonstrated. A fibrous scar was formed on a limited area of the trigeminal root. There were no signs of axonal regeneration, posttraumatic neuroma, or considerable changes in the Meekel sinus.