(6aR,10aR)-3-ethyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol | 134840-81-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: (6aR,10aR)-3-ethyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
• 英文别名: Ethyl-delta-9-tetrahydrocannabinol；(6aR,10aR)-3-ethyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol
• CAS: 134840-81-6
• 化学式: C₁₈H₂₄O₂
• 分子量: 272.387
• InChiKey: JJBMVXFZSLTKCL-ZIAGYGMSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3,5-dihydroxy-4-((1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-enyl)phenyl trifluoromethanesulfonate 在 三异丁基铝 、 三乙胺 、 zinc dibromide 作用下， 以 四氢呋喃 、 正己烷 、 二氯甲烷 为溶剂， 反应 22.5h， 生成 (6aR,10aR)-3-ethyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
  参考文献：
  名称：

  [EN] CATALYTIC TETRAHYDROCANNABINOL SYNTHESIS AND PRECURSORS
  [FR] SYNTHÈSE ET PRÉCURSEURS CATALYTIQUES DE TÉTRAHYDROCANNABINOL

  摘要：

  The present disclosure provides new tetrahydrocannabinol precursor compounds and processes to prepare tetrahydrocannabinol compounds. The disclosure also relates to the use of catalysts and catalytic processes for the preparation of tetrahydrocannabinol compounds from the tetrahydrocannabinol precursors. Compounds provided are of formula (I) and (II).

  公开号：

  WO2023102655A1

文献信息

• [EN] CATALYTIC CANNABINOID PROCESSES AND PRECURSORS<br/>[FR] PROCÉDÉS ET PRÉCURSEURS DE CANNABINOÏDES CATALYTIQUES
  申请人：KARE CHEMICAL TECH INC

  公开号：WO2020232545A1

  公开（公告）日：2020-11-26

  The present disclosure relates to new cannabinoid sulfonate esters and processes for their use to prepare cannabinoids. The disclosure also relates to the use of catalysts and catalytic processes for the preparation of cannabinoids from the cannabinoid sulfonate esters.

  本公开涉及新的大麻素磺酸酯和它们的制备大麻素的过程。该公开还涉及使用催化剂和催化过程从大麻素磺酸酯制备大麻素。
• CATALYTIC CANNABINOID PROCESSES AND PRECURSORS
  申请人：KARE CHEMICAL TECHNOLOGIES INC.

  公开号：US20220220089A1

  公开（公告）日：2022-07-14

  The present disclosure relates to new cannabinoid sulfonate esters and processes for their use to prepare cannabinoids. The disclosure also relates to the use of catalysts and catalytic processes for the preparation of cannabinoids from the cannabinoid sulfonate esters.
• [EN] CATALYTIC TETRAHYDROCANNABINOL SYNTHESIS AND PRECURSORS<br/>[FR] SYNTHÈSE ET PRÉCURSEURS CATALYTIQUES DE TÉTRAHYDROCANNABINOL
  申请人：[en]KARE CHEMICAL TECHNOLOGIES INC.

  公开号：WO2023102655A1

  公开（公告）日：2023-06-15

  The present disclosure provides new tetrahydrocannabinol precursor compounds and processes to prepare tetrahydrocannabinol compounds. The disclosure also relates to the use of catalysts and catalytic processes for the preparation of tetrahydrocannabinol compounds from the tetrahydrocannabinol precursors. Compounds provided are of formula (I) and (II).