7-(2-Methylprop-2-enoylamino)heptylphosphonic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: 7-(2-Methylprop-2-enoylamino)heptylphosphonic acid
• 英文别名: 7-(2-methylprop-2-enoylamino)heptylphosphonic acid
• 化学式: C₁₁H₂₂NO₄P
• 分子量: 263.27
• InChiKey: LHYGOWBZDBVEBM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  17
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  86.6
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• METHOD AND SYSTEM FOR FABRICATING DNA SEQUENCING ARRAYS
  申请人：Centrillion Technology Holdings Corporation

  公开号：EP3768881A1

  公开（公告）日：2021-01-27
• [EN] METHOD AND SYSTEM FOR FABRICATING DNA SEQUENCING ARRAYS<br/>[FR] PROCÉDÉ ET SYSTÈME DE FABRICATION DE RÉSEAUX DE SÉQUENÇAGE D'ADN
  申请人：CENTRILLION TECH INC

  公开号：WO2019183272A1

  公开（公告）日：2019-09-26

  The present disclosure relates to processes for inverting oligonucleotide probes in an in situ synthesized array. These processes can be used to reverse the orientation of probes with respect to the substrate from 3'-bound to a substrate to 5'-bound to another substrate. These processes can also be used to reduce or eliminate the presence of truncated probe sequences from an in situ synthesized array. These processes can preserve the original patterns of the synthesized oligonucleotide after the inversion. These process can be achieved via the formation of a hydrogel layer in-between a donor substrate and an acceptor substrate through a polymerization reaction forming the hydrogel layer.