Ethyl thiane-4-carboximidate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻烷
• 英文名称: Ethyl thiane-4-carboximidate
• 英文别名: ethyl thiane-4-carboximidate
• 化学式: C₈H₁₅NOS
• 分子量: 173.28
• InChiKey: SGUZHYQXWMQHLP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  58.4
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• IMIDAZOPIPERAZINONE INHIBITORS OF TRANSCRIPTION ACTIVATING PROTEINS
  申请人：Board of Regents, The University of Texas System

  公开号：US20190308978A1

  公开（公告）日：2019-10-10

  The present disclosure relates to heterocyclic compounds and methods which may be useful as inhibitors of transcription activating proteins such as CBP and P300 for the treatment or prevention of diseases such as proliferative diseases, inflammatory disorders, autoimmune diseases, and fibrotic diseases.

  本公开涉及可能用作转录激活蛋白如CBP和P300的抑制剂，用于治疗或预防诸如增殖性疾病、炎症性疾病、自身免疫疾病和纤维化疾病的异环化合物和方法。
• [EN] IMIDAZOPIPERAZINONE INHIBITORS OF TRANSCRIPTION ACTIVATING PROTEINS<br/>[FR] INHIBITEURS D'IMIDAZOPIPÉRAZINONE DE PROTÉINES D'ACTIVATION DE LA TRANSCRIPTION
  申请人：UNIV TEXAS

  公开号：WO2019195846A1

  公开（公告）日：2019-10-10

  The present disclosure relates to heterocyclic compounds and methods which may be useful as inhibitors of transcription activating proteins such as CBP and P300 for the treatment or prevention of diseases such as proliferative diseases, inflammatory disorders, autoimmune diseases, and fibrotic diseases.