1-Oxo-1,2,3,4-tetrahydro-naphthalene-2-sulfonic acid methylamide | 96856-08-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: 1-Oxo-1,2,3,4-tetrahydro-naphthalene-2-sulfonic acid methylamide
• 英文别名: N-methyl-1-oxo-3,4-dihydro-2H-naphthalene-2-sulfonamide
• CAS: 96856-08-5
• 化学式: C₁₁H₁₃NO₃S
• 分子量: 239.295
• InChiKey: QCPADTBNDCTAOS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  71.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  甲基氨基磺酰氯 以50%的产率得到
  参考文献：
  名称：

  BENDER, A.;GUENTHER, D.;WILLMS, L.;WINGEN, R., SYNTHESIS, BRD, 1985, N 1, 66-70

  摘要：

  DOI：

文献信息

• Synthesis and reactivity of N-alkyl-2-oxoalkanesulfonamides
  作者：Juan A. Vega、Ramón Alajarín、Juan J. Vaquero、Julio Alvarez-Builla

  DOI：10.1016/s0040-4020(98)00093-3

  日期：1998.4

  A series of N-alkyl-2-oxoalkanesulfonamides have been synthesized by reacting silyl enol ethers with N-alkyl-sulfamoyl chlorides. Their reactivity towards electrophiles was investigated in order to explore the regio-and stereoselectivity of the process. 2-Oxoalkanesulfonamides were used to prepare 5-(methylsulfamoyl)-1,4-dihydropyridines derivatives. (C) 1998 Elsevier Science Ltd. All rights reserved.
• Improved method for the synthesis of N-methyl-2-oxoalkanesulfonamides.
  作者：Juan A. Vega、Andrés Molina、Ramón Alajarín、Juan J. Vaquero、José L.García Navío、Julio Alvarez-Builla

  DOI：10.1016/s0040-4039(00)92534-6

  日期：1992.6

  A series of N-methyl-2-oxoalkanesulfonamides was prepared by reaction between silyl enol ethers and N-methylsulfonylimine. In all cases yields were comparatively higher to those obtained by a previously described procedure
• Eine einfache Synthese von 2-Oxoalkansulfonamiden
  作者：Albert Bender、Dieter Günther、Lothar Willms、Rainer Wingen

  DOI：10.1055/s-1985-31109

  日期：——