2-Sulfanylcyclohexane-1-carbonitrile

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-Sulfanylcyclohexane-1-carbonitrile
• 英文别名: 2-sulfanylcyclohexane-1-carbonitrile
• 化学式: C₇H₁₁NS
• 分子量: 141.24
• InChiKey: BUSXKSULXYDVFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  24.8
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• BORON CONTAINING PYRAZOLE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF
  申请人：Boehringer Ingelheim Animal Health USA Inc.

  公开号：US20220194965A1

  公开（公告）日：2022-06-23

  The present invention describes novel boron containing pyrazole compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the invention have activity as Janus kinase (JAK) inhibitors and are useful in the in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described are methods of treating inflammation, auto-immune diseases, cancer, and other conditions that are susceptible to the inhibition of a Janus kinase by administering a compound herein described.