6,7-diethoxy-1,3-dimethyl-isoquinoline

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: 6,7-diethoxy-1,3-dimethyl-isoquinoline
• 英文别名: 6,7-Diaethoxy-1,3-dimethyl-isochinolin；6,7-Diethoxy-1,3-dimethylisoquinoline；6,7-diethoxy-1,3-dimethylisoquinoline
• 化学式: C₁₅H₁₉NO₂
• 分子量: 245.321
• InChiKey: YDXDDKGEEVVKPN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  31.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 氯仿 、 三氯氧磷 作用下， 生成 6,7-diethoxy-1,3-dimethyl-isoquinoline
  参考文献：
  名称：

  Bruckner et al., Journal of the Chemical Society, 1948, p. 885,889

  摘要：

  DOI：

文献信息

• Bruckner; Kovacs; Kovacs, Chemische Berichte, 1944, vol. 77/79, p. 610,616
  作者：Bruckner、Kovacs、Kovacs

  DOI：——

  日期：——
• The price of peace: the personal and financial cost of paramilitary punishments in Northern Ireland
  作者：P.C Nolan、J McPherson、R McKeown、H Diaz、D Wilson

  DOI：10.1016/s0020-1383(99)00197-7

  日期：2000.1

  The aim of this study was to compare the injuries sustained during paramilitary punishments both before and after the onset of "peace" in Northern Ireland. A retrospective chart review was performed looking at age, injuries, treatments instituted, theatre time, length of hospital stay and overall cost of care. In the 10-month period before the ceasefire, 31 patients were treated after sustaining paramilitary punishment shootings. Mean age was 25.2 years. All patients had small entrance and exit wounds with minimal soft tissue disruption. A total of 18 fractures were recorded in 15 patients and 14 arteries required repair. Mean operative time was 2.6 h, mean hospital stay 7.61 days and mean cost per patient pound 3102. In the following 10-month period 28 patients were admitted after punishments, only one of whom had been shot, all others had been beaten with sticks and clubs. Mean age was 27.4 years. In 52 limbs, 64 fractures were recorded and 44% of these were open; 15 of the fractures were Gustilo and Anderson Grade III or greater and 11 of the fractures were intra-articular. There were no arterial injuries. Mean operative time was 2.6 h, mean hospital stay 12.4 h and mean cost per patient pound 3849. (C) 2000 Elsevier Science Ltd. All rights reserved.